Negligible impact of rare autoimmune-locus coding-region variants on missing heritability
Karen A. Hunt(Queen Mary University of London), David A. van Heel(Queen Mary University of London), Francesca Capon(King's College London), Monkol Lek(Massachusetts General Hospital), Charles A. Mein(Queen Mary University of London), Yong Kong(W. M. Keck Foundation), Jack Satsangi(Nuffield Orthopaedic Centre), Christopher G. Mathew(National Health Laboratory Service), Michael A. Simpson(King's College London), Richard C. Trembath(King's College London), John Mansfield(Newcastle University), Oliver S. Burren(AstraZeneca (United Kingdom)), Jeffrey C. Barrett(Wellcome Sanger Institute), Maria Ban(University of Cambridge), Matthew J. Simmonds(University of Birmingham), Luke Jostins(Wellcome Sanger Institute), Eva Wozniak(Queen Mary University of London), Stephan Brand(Charles River Laboratories (United Kingdom)), Nicholas Bockett(Queen Mary University of London), Sarah Nutland(University of Cambridge), Miles Parkes(Cambridge University Hospitals NHS Foundation Trust), Vincent Plagnol(University College London), Tariq Ahmad(National Health Service), Stephen S. Rich(Virginia Department of Health), Neil Walker, Alastair Compston(University of Cambridge), Efterpi Papouli(King's College London), Suna Önengüt-Gümüşcü(University of Virginia), James Lee(Royal Free London NHS Foundation Trust), Stephen Gough(Bond University), Hannah Blackburn(Wellcome Sanger Institute), Vanisha Mistry(Queen Mary University of London), Steven Sawcer(University of Cambridge), John A. Todd(University of Oxford), Muddassar M. Mirza(Genomics England), Daniel G. MacArthur(Garvan Institute of Medical Research)
Cited by 189
Related Papers
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
|Nature|2007|9.6k
Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
|Nature|2012|4.8k
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
|Nature Genetics|2015|2.8k
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
|Nature Genetics|2008|2.6k