Suppressing β3-integrin triggers a neuropilin-1 dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesis
Tim Ellison(University of East Anglia), Stephen D. Robinson(University of East Anglia)
Cited by 23
Related Papers
Endothelial neuropilin‐2 influences angiogenesis by regulating actin pattern development and α5‐integrin‐ <i>p</i> ‐FAK complex recruitment to assembling adhesion sites
|The FASEB Journal|2021|43
A proteomics approach to isolating neuropilin-dependent α5 integrin trafficking pathways: neuropilin 1 and 2 co-traffic α5 integrin through endosomal p120RasGAP to promote polarised fibronectin fibrillogenesis in endothelial cells
|Communications Biology|2024|6
Endothelial NRP2 influences angiogenesis by regulating actin pattern development and α5-integrin- <i>p</i> -FAK complex recruitment to assembling adhesion sites
|bioRxiv (Cold Spring Harbor Laboratory)|2021|0
Together, Neuropilin 1 and Neuropilin 2 direct α5 integrin trafficking through GTPase-activating-protein p120RasGAP in endothelial cells to promote fibronectin fibrillogenesis
|bioRxiv (Cold Spring Harbor Laboratory)|2023|0