An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

Carson C. Thoreen(Howard Hughes Medical Institute), Nathanael S. Gray(Stanford University)

Journal of Biological Chemistry

January 17, 2009

10.1074/jbc.m900301200

Cited by 1,803

Related Papers

Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors

|Nature Chemical Biology|2016|368

Development of Selective Covalent Janus Kinase 3 Inhibitors

|Journal of Medicinal Chemistry|2015|115

Development of PDE6D and CK1α Degraders through Chemical Derivatization of FPFT-2216

|Journal of Medicinal Chemistry|2021|55

Selective Akt Inhibitors Synergize with Tyrosine Kinase Inhibitors and Effectively Override Stroma-Associated Cytoprotection of Mutant FLT3-Positive AML Cells

|PLoS ONE|2013|42

Development of potent and selective degraders of PI5P4Kγ

|European Journal of Medicinal Chemistry|2022|11