neXtProt: a knowledge platform for human proteins

Lydie Lane, Ghislaine Argoud‐Puy(SIB Swiss Institute of Bioinformatics), Aurore Britan(SIB Swiss Institute of Bioinformatics), Isabelle Cusin(SIB Swiss Institute of Bioinformatics), Paula Duek(SIB Swiss Institute of Bioinformatics), Olivier Evalet(SIB Swiss Institute of Bioinformatics), Alain Gateau(SIB Swiss Institute of Bioinformatics), Pascale Gaudet(SIB Swiss Institute of Bioinformatics), Anne Gleizes(SIB Swiss Institute of Bioinformatics), Alexandre Masselot(SIB Swiss Institute of Bioinformatics), Catherine Zwahlen(SIB Swiss Institute of Bioinformatics), Amos Bairoch(SIB Swiss Institute of Bioinformatics)
Nucleic Acids Research
December 1, 2011
10.1093/nar/gkr1179
Cited by 198Open Access
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Abstract

neXtProt (http://www.nextprot.org/) is a new human protein-centric knowledge platform. Developed at the Swiss Institute of Bioinformatics (SIB), it aims to help researchers answer questions relevant to human proteins. To achieve this goal, neXtProt is built on a corpus containing both curated knowledge originating from the UniProtKB/Swiss-Prot knowledgebase and carefully selected and filtered high-throughput data pertinent to human proteins. This article presents an overview of the database and the data integration process. We also lay out the key future directions of neXtProt that we consider the necessary steps to make neXtProt the one-stop-shop for all research projects focusing on human proteins.

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