Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

Sebastian Bender; Yujie Tang; Anders M. Lindroth; Volker Hovestadt; David Jones; Marcel Kool; Marc Zapatka; Paul A. Northcott; Dominik Sturm; Wei Wang; Bernhard Radlwimmer; Jonas W. Højfeldt; Nathalène Truffaux; David Castel; Simone Schubert; Marina Ryzhova; Huriye Seker‐Cin; Jan Gronych; Pascal D. Johann; Sebastian Stark; Jochen Meyer; Till Milde; Martin U. Schuhmann; Martin Ebinger; Camelia‐Maria Monoranu; Anitha Ponnuswami; Spenser Chen; Chris Jones; Olaf Witt; V. Peter Collins; Andreas von Deimling; Nada Jabado; Stéphanie Puget; Jacques Grill; Kristian Helin; Andrey Korshunov; Peter Lichter; Michelle Monje; Christoph Plass; Yoon-Jae Cho; Stefan M. Pfister

doi:10.1016/j.ccr.2013.10.006

Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

Sebastian Bender(German Cancer Research Center), Yujie Tang(Stanford University), Anders M. Lindroth(German Cancer Research Center), Volker Hovestadt(German Cancer Research Center), David Jones(German Cancer Research Center), Marcel Kool(German Cancer Research Center), Marc Zapatka(German Cancer Research Center), Paul A. Northcott(German Cancer Research Center), Dominik Sturm(German Cancer Research Center), Wei Wang(German Cancer Research Center), Bernhard Radlwimmer(German Cancer Research Center), Jonas W. Højfeldt(University of Copenhagen), Nathalène Truffaux(Université Paris-Sud), David Castel(Université Paris-Sud), Simone Schubert(Stanford University), Marina Ryzhova(Burdenko Neurosurgery Institute), Huriye Seker‐Cin(German Cancer Research Center), Jan Gronych(German Cancer Research Center), Pascal D. Johann(German Cancer Research Center), Sebastian Stark(German Cancer Research Center), Jochen Meyer(German Cancer Research Center), Till Milde(German Cancer Research Center), Martin U. Schuhmann(University Children's Hospital Tübingen), Martin Ebinger(University Children's Hospital Tübingen), Camelia‐Maria Monoranu(University of Würzburg), Anitha Ponnuswami(Stanford University), Spenser Chen(Stanford University), Chris Jones(Institute of Cancer Research), Olaf Witt(German Cancer Research Center), V. Peter Collins(University of Cambridge), Andreas von Deimling(German Cancer Research Center), Nada Jabado(McGill University Health Centre), Stéphanie Puget(Hôpital Necker-Enfants Malades), Jacques Grill(Université Paris-Sud), Kristian Helin(University of Copenhagen), Andrey Korshunov(German Cancer Research Center), Peter Lichter(German Cancer Research Center), Michelle Monje(Stanford University), Christoph Plass(German Cancer Research Center), Yoon-Jae Cho(Stanford University), Stefan M. Pfister(German Cancer Research Center)

Cancer Cell

October 31, 2013

10.1016/j.ccr.2013.10.006

Cited by 838Open Access

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