Data integration in the era of omics: current and future challenges

David Gómez-Cabrero(Karolinska Institutet), Imad Abugessaisa(Karolinska Institutet), Dieter Maier(Biomax Informatics (Germany)), Andrew E. Teschendorff(Cancer Institute (WIA)), Matthias Merkenschlager(Imperial College London), Andreas Gisel(Institute of Biomedical Technologies), Esteban Ballestar(Institut d'Investigació Biomédica de Bellvitge), Erik Bongcam‐Rudloff(Swedish University of Agricultural Sciences), Ana Conesa(Centro de Investigacion Principe Felipe), Jesper Tegnér(Karolinska Institutet)
BMC Systems Biology
January 1, 2014
Cited by 423Open Access
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Abstract

To integrate heterogeneous and large omics data constitutes not only a conceptual challenge but a practical hurdle in the daily analysis of omics data. With the rise of novel omics technologies and through large-scale consortia projects, biological systems are being further investigated at an unprecedented scale generating heterogeneous and often large data sets. These data-sets encourage researchers to develop novel data integration methodologies. In this introduction we review the definition and characterize current efforts on data integration in the life sciences. We have used a web-survey to assess current research projects on data-integration to tap into the views, needs and challenges as currently perceived by parts of the research community.


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