JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update

Jan Christian Bryne(University of Bergen), Eivind Valen(Technical University of Denmark), Man‐Hung Eric Tang(Technical University of Denmark), Troels Marstrand(Technical University of Denmark), Ole Winther(Technical University of Denmark), Isabelle da Piedade(Technical University of Denmark), Anders Krogh(Technical University of Denmark), Boris Lenhard(Technical University of Denmark), Albin Sandelin(Technical University of Denmark)
Nucleic Acids Research
November 15, 2007
Cited by 689Open Access
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Abstract

JASPAR is a popular open-access database for matrix models describing DNA-binding preferences for transcription factors and other DNA patterns. With its third major release, JASPAR has been expanded and equipped with additional functions aimed at both casual and power users. The heart of the JASPAR database-the JASPAR CORE sub-database-has increased by 12% in size, and three new specialized sub-databases have been added. New functions include clustering of matrix models by similarity, generation of random matrices by sampling from selected sets of existing models and a language-independent Web Service applications programming interface for matrix retrieval. JASPAR is available at http://jaspar.genereg.net.


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