Matching to Remove Bias in Observational Studies

Abstract

: Several matching methods that match all of one sample from another larger sample on a continuous matching variable are compared with respect to their ability to remove the bias of the matching variable. One method is a simple mean-matching method and three are nearest available pair-matching methods. The methods' abilities to remove bias are also compared with the theoretical maximum given fixed distributions and fixed sample sizes. A summary of advice to an investigator is included.