Brain Serotonin Concentration: Elevation Following Intraperitoneal Administration of Melatonin

Fernando Antón‐Tay(Massachusetts Institute of Technology), Chuan Chou(Massachusetts Institute of Technology), S.M. Anton(Massachusetts Institute of Technology), Richard J. Wurtman(Massachusetts Institute of Technology)
Science
October 11, 1968
Cited by 250

Abstract

The intraperitoneal administration of melatonin to rats caused an increase in brain serotonin concentration, especially in the midbrain. This effect could be demonstrated within 20 minutes of melatonin administration and was not associated with changes in norepinephrine concentration.


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