Cloning and sequence analysis of cDNA encoding the precursor of a human endothelium‐derived vasoconstrictor peptide, endothelin: Identity of human and porcine endothelin

Yasuaki Itoh; Masashi Yanagisawa; Shoichi Ohkubo; Chiharu Kimura; Takuo Kosaka; Akihiro Inoue; Norio Ishida; Youji Mitsui; Haruo Onda; Masahiko Fujino; Tomoh Masaki

doi:10.1016/0014-5793(88)80867-6

Cloning and sequence analysis of cDNA encoding the precursor of a human endothelium‐derived vasoconstrictor peptide, endothelin: Identity of human and porcine endothelin

Yasuaki Itoh(Takeda (Japan)), Masashi Yanagisawa(University of Tsukuba), Shoichi Ohkubo(Takeda (Japan)), Chiharu Kimura(Takeda (Japan)), Takuo Kosaka(Takeda (Japan)), Akihiro Inoue(University of Tsukuba), Norio Ishida(Institute for Fermentation), Youji Mitsui(Institute for Fermentation), Haruo Onda(Takeda (Japan)), Masahiko Fujino(Takeda (Japan)), Tomoh Masaki(University of Tsukuba)

FEBS Letters

April 25, 1988

10.1016/0014-5793(88)80867-6

Cited by 401Open Access

Full Text

Abstract

A cDNA encoding a human endothelium-derived vasoconstrictor peptide, endothelin, was isolated from a human placenta cDNA library. The nucleotide sequence of this cDNA clone showed that the primary structure of the human preproendothelin has 212 amino acid residues and is highly homologous to porcine preproendothelin, and that human endothelin is identical with porcine endothelin.

Related Papers

No related papers found

Powered by citation graph analysis