Plants and animals share functionally common bacterial virulence factors
Laurence G. Rahme(Harvard University), Frederick M. Ausubel(Harvard University), Hui Cao(Harvard University), Eliana Drenkard(Harvard University), Boyan C. Goumnerov(Harvard University), Gee W. Lau(Harvard University), Shalina Mahajan‐Miklos(Harvard University), Julia M. Plotnikova(Harvard University), Man-Wah Tan(Harvard University), John Tsongalis(Harvard University), Cynthia L. Walendziewicz(Harvard University), Ronald G. Tompkins(Harvard University)
Cited by 411Open Access
Abstract
By exploiting the ability of Pseudomonas aeruginosa to infect a variety of vertebrate and nonvertebrate hosts, we have developed model systems that use plants and nematodes as adjuncts to mammalian models to help elucidate the molecular basis of P. aeruginosa pathogenesis. Our studies reveal a remarkable degree of conservation in the virulence mechanisms used by P. aeruginosa to infect hosts of divergent evolutionary origins.
Related Papers
No related papers found
Powered by citation graph analysis