Mutations in the SIX1/2 Pathway and the DROSHA/DGCR8 miRNA Microprocessor Complex Underlie High-Risk Blastemal Type Wilms Tumors

Jenny Wegert; Naveed Ishaque; Romina Vardapour; Christina Geörg; Zuguang Gu; Matthias Bieg; Barbara Ziegler; Sabrina Bausenwein; Nasenien Nourkami; Nicole Ludwig; Andreas Keller; Clemens Grimm; Susanne Kneitz; Richard D. Williams; Tas Chagtai; Kathy Pritchard‐Jones; Peter van Sluis; Richard Volckmann; Jan Köster; Rogier Versteeg; Tomás Acha; Maureen J. O’Sullivan; Peter K. Bode; Felix Niggli; Godelieve A.M. Tytgat; Harm van Tinteren; Marry M. van den Heuvel‐Eibrink; Eckart Meese; Christian Vokuhl; Ivo Leuschner; Norbert Graf; Roland Eils; Stefan M. Pfister; Marcel Kool; Manfred Gessler

doi:10.1016/j.ccell.2015.01.002

Mutations in the SIX1/2 Pathway and the DROSHA/DGCR8 miRNA Microprocessor Complex Underlie High-Risk Blastemal Type Wilms Tumors

Jenny Wegert(Comprehensive Cancer Center Mainfranken), Naveed Ishaque(German Cancer Research Center), Romina Vardapour(Comprehensive Cancer Center Mainfranken), Christina Geörg(Heidelberg University), Zuguang Gu(German Cancer Research Center), Matthias Bieg(German Cancer Research Center), Barbara Ziegler(Comprehensive Cancer Center Mainfranken), Sabrina Bausenwein(Comprehensive Cancer Center Mainfranken), Nasenien Nourkami(Saarland University), Nicole Ludwig(Saarland University), Andreas Keller(Saarland University), Clemens Grimm(University of Würzburg), Susanne Kneitz(University of Würzburg), Richard D. Williams(University College London), Tas Chagtai(University College London), Kathy Pritchard‐Jones(University College London), Peter van Sluis(Academic Medical Center), Richard Volckmann(University of Amsterdam), Jan Köster(Academic Medical Center), Rogier Versteeg(University of Amsterdam), Tomás Acha(Hospital Materno-Infantil), Maureen J. O’Sullivan(Trinity College Dublin), Peter K. Bode(University Children's Hospital Zurich), Felix Niggli(University Children's Hospital Zurich), Godelieve A.M. Tytgat(Emma Kinderziekenhuis), Harm van Tinteren(University of Amsterdam), Marry M. van den Heuvel‐Eibrink(Erasmus MC), Eckart Meese(Saarland University), Christian Vokuhl(Kiel University), Ivo Leuschner(Kiel University), Norbert Graf(Saarland University), Roland Eils(Heidelberg University), Stefan M. Pfister(Heidelberg University), Marcel Kool(German Cancer Research Center), Manfred Gessler(Comprehensive Cancer Center Mainfranken)

Cancer Cell

February 1, 2015

10.1016/j.ccell.2015.01.002

Cited by 306

Abstract

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