Pharmacology of a Central Nervous System Delivered 2′-O-Methoxyethyl–Modified Survival of Motor Neuron Splicing Oligonucleotide in Mice and Nonhuman Primates

Frank Rigo; Seung Chun; Daniel A. Norris; Gene Hung; Sam Lee; John Matson; Robert Fey; Hans Gaus; Yimin Hua; John S. Grundy; Adrian R. Krainer; Scott P. Henry; C. Frank Bennett

doi:10.1124/jpet.113.212407

Pharmacology of a Central Nervous System Delivered 2′-O-Methoxyethyl–Modified Survival of Motor Neuron Splicing Oligonucleotide in Mice and Nonhuman Primates

Frank Rigo(Ionis Pharmaceuticals (United States)), Seung Chun(Ionis Pharmaceuticals (United States)), Daniel A. Norris(Cold Spring Harbor Laboratory), Gene Hung(Ionis Pharmaceuticals (United States)), Sam Lee(Cold Spring Harbor Laboratory), John Matson(Cold Spring Harbor Laboratory), Robert Fey(Ionis Pharmaceuticals (United States)), Hans Gaus(Cold Spring Harbor Laboratory), Yimin Hua(Cold Spring Harbor Laboratory), John S. Grundy(Ionis Pharmaceuticals (United States)), Adrian R. Krainer(Ionis Pharmaceuticals (United States)), Scott P. Henry(Cold Spring Harbor Laboratory), C. Frank Bennett(Cold Spring Harbor Laboratory)

Journal of Pharmacology and Experimental Therapeutics

May 1, 2014

10.1124/jpet.113.212407

Cited by 275Open Access

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