Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Gillian M. Tannahill(Trinity College Dublin), Annie M. Curtis(Trinity College Dublin), Juraj Adamik(Duquesne University), Eva M. Pålsson‐McDermott(Trinity College Dublin), Anne F. McGettrick(Trinity College Dublin), Gautam Goel(Massachusetts General Hospital), Christian Frezza(Medical Research Council), Nicholas J. Bernard(Trinity College Dublin), Beth Kelly(Trinity College Dublin), Niamh H. Foley(Trinity College Dublin), Liang Zheng(Cancer Research UK Scotland Institute), Agnès Gardet(Broad Institute), Zhen Tong(Cornell University), S. S. Jany(Trinity College Dublin), Sinéad C. Corr(Trinity College Dublin), Moritz Haneklaus(Trinity College Dublin), Brian E. Caffrey(Trinity College Dublin), Kerry A. Pierce(Broad Institute), Sarah R. Walmsley(University of Sheffield), Federico C. Beasley(University of California, San Diego), Eoin P. Cummins(University College Dublin), Victor Nizet(University of California, San Diego), Moira K. B. Whyte(University of Sheffield), Cormac T. Taylor(University College Dublin), Hening Lin(Cornell University), Seth L. Masters(Walter and Eliza Hall Institute of Medical Research), Eyal Gottlieb(Cancer Research UK Scotland Institute), Vincent P. Kelly(Trinity College Dublin), Clary B. Clish(Broad Institute), Philip E. Auron(Duquesne University), Ramnik J. Xavier(Hutchison/MRC Research Centre), Luke O'neill(Trinity College Dublin)

Nature

March 22, 2013

Cited by 3,921Open Access

Abstract