Crystal Structure of Hck in Complex with a Src Family–Selective Tyrosine Kinase Inhibitor

Thomas H. Schindler(University Hospital of Geneva), John Kuriyan(Vanderbilt University), Aviv Gazit(Hebrew University of Jerusalem), Frank Sicheri(University of Toronto), Alexander R. Pico(Gladstone Institutes), A Levitzki(Hebrew University of Jerusalem)

Molecular Cell

May 1, 1999

10.1016/s1097-2765(00)80357-3

Cited by 426

Related Papers

Crystallographic <i>R</i> Factor Refinement by Molecular Dynamics

|Science|1987|2k

Structural Mechanism for STI-571 Inhibition of Abelson Tyrosine Kinase

|Science|2000|1.8k

The Conformational Plasticity of Protein Kinases

|Cell|2002|1.8k

An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor

|Cell|2006|1.6k

Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia

|Cancer Cell|2002|1.6k