Eukaryotic DNA Polymerases: Proposal for a Revised Nomenclature
Peter Burgers(Washington University in St. Louis), Eugene V. Koonin(National Center for Biotechnology Information), Elspeth A. Bruford(UCL Australia), Luis Blanco(Centro de Biología Molecular Severo Ochoa), Kenneth C. Burtis(University of California, Davis), Michael F. Christman(University of Virginia), William C. Copeland(National Institute of Environmental Health Sciences), Errol C. Friedberg(The University of Texas Southwestern Medical Center), Fumio Hanaoka(Osaka University), David C. Hinkle(University of Rochester), Christopher W. Lawrence(University of Rochester), Makoto Nakanishi(Nagoya City University), Haruo Ohmori(Kyoto University of Education), Louise Prakash(The University of Texas Medical Branch at Galveston), Satya Prakash(The University of Texas Medical Branch at Galveston), Claude–Agnès Reynaud(Université Paris Cité), Akio Sugino(Osaka University), Takeshi Todo(Kyoto University), Zhigang Wang(University of Kentucky), Jean-Claude Weill(Institut Necker Enfants Malades), Roger Woodgate(Eunice Kennedy Shriver National Institute of Child Health and Human Development)
Cited by 334Open Access
Abstract
Pol polymeraseIn 1975, a Greek letter nomenclature system was introduced to designate DNA polymerases from mammalian cells (1). Ten years ago, progress in the biochemical analysis of eukaryotic DNA polymerases and in the isolation of their genes, particularly in the yeast Saccharomyces cerevisiae, necessitated a revision of the Greek letter nomenclature system and an expansion to include all eukaryotic organisms (2). Until a few years ago, this system sufficed to designate the six known DNA polymerases α, β, γ, δ, ε, and ζ.
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