Acute axonal polyneuropathy associated with anti‐GM <sub>1</sub> antibodies following <i>Campylobacter enteritis</i>

Nobuhiro Yuki(Niigata University), Hiide Yoshino(Niigata University), Shuzo Sato(Niigata University), Tadashi Miyatake(Niigata University)
Neurology
December 1, 1990
Cited by 478

Abstract

We report 2 patients with Guillain-Barré syndrome (GBS) following Campylobacter jejuni enteritis. Electrophysiologic studies indicated that the predominant process was axonal degeneration of motor nerves, and clinical recovery was poor. Serum testing by thin-layer chromatography and enzyme-linked immunosorbent assay revealed that the sera from both patients contained high titers of IgG antibody against GM1 ganglioside. These cases may represent a subgroup of GBS as acute axonal polyneuropathy following C jejuni enteritis associated with anti-GM1 antibodies.


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