Discovery and Optimization of 1,3,4-Trisubstituted-pyrazolone Derivatives as Novel, Potent, and Nonsteroidal Farnesoid X Receptor (FXR) Selective Antagonists

Huang Huang(East China University of Science and Technology), Jian Li(Sir Run Run Shaw Hospital), Ruoqun Ma(East China University of Science and Technology), Xing Xu(Shanghai Jiao Tong University), Ying Yu(Wuhan University), Lili Chen(National Health Research Institutes), Yong Zhang(Hebei Medical University), Hui Jin(East China University of Science and Technology), Xu Shen(Chinese Academy of Sciences), Wenzhong Yan(East China University of Science and Technology), Zhenting Gao(East China University of Science and Technology), Hualiang Jiang(Chinese Academy of Sciences), Chenjing Li(Chinese Academy of Sciences), Jin Zhu(East China University of Science and Technology)
Journal of Medicinal Chemistry
August 3, 2012
10.1021/jm3002718
Cited by 63

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