A Shape-Based 3-D Scaffold Hopping Method and Its Application to a Bacterial Protein−Protein Interaction

Thomas S. Rush(AstraZeneca (United Kingdom)), Anthony Nicholls(AstraZeneca (United Kingdom)), Lidia Mosyak(Pfizer (United States)), Jennifer Grant(AstraZeneca (United Kingdom))

Journal of Medicinal Chemistry

February 10, 2005

10.1021/jm040163o

Cited by 605

Related Papers

Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses

|Nature|2001|484

The bacterial cell‐division protein ZipA and its interaction with an FtsZ fragment revealed by X‐ray crystallography

|The EMBO Journal|2000|277

Structural mechanism of ligand activation in human calcium-sensing receptor

|eLife|2016|263

Structural mechanism of ligand activation in human GABAB receptor

|Nature|2013|204

Crystal Structure of the Wild-type von Willebrand Factor A1-Glycoprotein Ibα Complex Reveals Conformation Differences with a Complex Bearing von Willebrand Disease Mutations

|Journal of Biological Chemistry|2004|203