Aptamers as molecular recognition elements for electrical nanobiosensors

Jeong-O Lee(Korea Research Institute of Chemical Technology), Hye‐Mi So(Korea Research Institute of Chemical Technology), Eun‐Kyoung Jeon(Korea Research Institute of Chemical Technology), Hyunju Chang(Korea Research Institute of Chemical Technology), Keehoon Won(Dongguk University), Yong Hwan Kim(Kwangwoon University)
Analytical and Bioanalytical Chemistry
October 22, 2007
Cited by 278Open Access
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Abstract

Recent advances in nanotechnology have enabled the development of nanoscale sensors that outperform conventional biosensors. This review summarizes the nanoscale biosensors that use aptamers as molecular recognition elements. The advantages of aptamers over antibodies as sensors are highlighted. These advantages are especially apparent with electrical sensors such as electrochemical sensors or those using field-effect transistors.


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