Clock Mutants of <i>Drosophila melanogaster</i>
Ronald J. Konopka(California Institute of Technology), Seymour Benzer(California Institute of Technology)
Cited by 2,290Open Access
Abstract
Three mutants have been isolated in which the normal 24-hour rhythm is drastically changed. One mutant is arrhythmic; another has a period of 19 hr; a third has a period of 28 hr. Both the eclosion rhythm of a population and the locomotor activity of individual flies are affected. All these mutations appear to involve the same functional gene on the X chromosome.
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