IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis

James E. Vince(La Trobe University), W. Wei‐Lynn Wong(La Trobe University), Nufail Khan(La Trobe University), Rebecca Feltham(La Trobe University), Diep Chau(La Trobe University), Afsar U. Ahmed(La Trobe University), Christopher A. Benetatos(TetraLogic Pharmaceuticals (United States)), Srinivas K. Chunduru(TetraLogic Pharmaceuticals (United States)), Stephen M. Condon(TetraLogic Pharmaceuticals (United States)), Mark A. McKinlay(TetraLogic Pharmaceuticals (United States)), Robert Brink(Garvan Institute of Medical Research), Martin Leverkus(Otto-von-Guericke-Universität Magdeburg), Vinay Tergaonkar(Institute of Molecular and Cell Biology), Pascal Schneider(University of Lausanne), Bernard A. Callus(La Trobe University), Frank Köentgen, David L. Vaux(La Trobe University), John Silke(La Trobe University)
Cell
November 1, 2007
10.1016/j.cell.2007.10.037
Cited by 1,063Open Access
Full Text

Abstract

Related Papers

Suppression of TNF-α-Induced Apoptosis by NF-κB
Daniel J. Van Antwerp, Séamus J. Martin, Tal Kafri et al.|Science|1996|2.6k
Activation by IKKα of a Second, Evolutionary Conserved, NF-κB Signaling Pathway
Uwe Senftleben, Yixue Cao, Gutian Xiao et al.|Science|2001|1.4k
The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins
Mike Rothe, Ming-Gui Pan, William J. Henzel et al.|Cell|1995|1.3k
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
Srinivasa M. Srinivasula, R.P. Hegde, Ayman Saleh et al.|Nature|2001|999
DNA Damaging Agents Induce Expression of Fas Ligand and Subsequent Apoptosis in T Lymphocytes via the Activation of NF-κB and AP-1
Shailaja Kasibhatla, Thomas Brunner, Laurent Genestier et al.|Molecular Cell|1998|727