Visualization of the intracellular location and stability of DNA origami with a label-free fluorescent probe

Xibo Shen; Qiao Jiang; Jin‐Ye Wang; Luru Dai; Guozhang Zou; Zhen‐Gang Wang; Weiqiang Chen; Wei Jiang; Baoquan Ding

doi:10.1039/c2cc36185j

Visualization of the intracellular location and stability of DNA origami with a label-free fluorescent probe

Xibo Shen(Shandong University), Qiao Jiang(National Center for Nanoscience and Technology), Jin‐Ye Wang(National Center for Nanoscience and Technology), Luru Dai(National Center for Nanoscience and Technology), Guozhang Zou(National Center for Nanoscience and Technology), Zhen‐Gang Wang(National Center for Nanoscience and Technology), Weiqiang Chen(Institute of Modern Physics), Wei Jiang(Shandong University), Baoquan Ding(National Center for Nanoscience and Technology)

Chemical Communications

January 1, 2012

10.1039/c2cc36185j

Cited by 122

Abstract

We report a label-free fluorescent strategy to study the distribution and stability of DNA origami nanostructures in live, cellular systems, using carbazole-based biscyanine as a probe molecule which has the characteristic property of restriction of intramolecular rotation (RIR) induced emission.

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