Eight Calves Cloned from Somatic Cells of a Single Adult
Yōkō Kato(Institute for Animal Reproduction), T. Tani(Institute for Animal Reproduction), Yusuke Sotomaru(Institute for Animal Reproduction), Kazuo Kurokawa(Institute for Animal Reproduction), Jun‐ya Kato(Institute for Animal Reproduction), Hiroshi Doguchi(Institute for Animal Reproduction), Hiroshi Yasue(Institute for Animal Reproduction), Yukio Tsunoda(Institute for Animal Reproduction)
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Abstract
Eight calves were derived from differentiated cells of a single adult cow, five from cumulus cells and three from oviductal cells out of 10 embryos transferred to surrogate cows (80 percent success). All calves were visibly normal, but four died at or soon after birth from environmental causes, and postmortem analysis revealed no abnormality. These results show that bovine cumulus and oviductal epithelial cells of the adult have the genetic content to direct the development of newborn calves.
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