<i>Arabidopsis</i> Transcription Factors: Genome-Wide Comparative Analysis Among Eukaryotes

José Luis Riechmann(Mendel Biotechnology (United States)), Jacqueline E. Heard(Mendel Biotechnology (United States)), Greg S. Martin(Mendel Biotechnology (United States)), T. Lynne Reuber(Mendel Biotechnology (United States)), Cai‐Zhong Jiang(Mendel Biotechnology (United States)), James S. Keddie(Mendel Biotechnology (United States)), Luc Adam(Mendel Biotechnology (United States)), Omaira Pineda(Mendel Biotechnology (United States)), Oliver J. Ratcliffe(Mendel Biotechnology (United States)), Raymond R. Samaha(Mendel Biotechnology (United States)), Robert A. Creelman(Mendel Biotechnology (United States)), Marsha L. Pilgrim(Mendel Biotechnology (United States)), Pierre Broun(Mendel Biotechnology (United States)), J. Z. Zhang(Mendel Biotechnology (United States)), D. Ghandehari(Mendel Biotechnology (United States)), Bjorg Sherman(Mendel Biotechnology (United States)), Guorong Yu(Mendel Biotechnology (United States))
Science
December 15, 2000
Cited by 2,864

Abstract

The completion of the Arabidopsis thaliana genome sequence allows a comparative analysis of transcriptional regulators across the three eukaryotic kingdoms. Arabidopsis dedicates over 5% of its genome to code for more than 1500 transcription factors, about 45% of which are from families specific to plants. Arabidopsis transcription factors that belong to families common to all eukaryotes do not share significant similarity with those of the other kingdoms beyond the conserved DNA binding domains, many of which have been arranged in combinations specific to each lineage. The genome-wide comparison reveals the evolutionary generation of diversity in the regulation of transcription.


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