The International HapMap Project
Richard A. Gibbs(Baylor College of Medicine), John W. Belmont, Paul Hardenbol, T. D. Willis(Baylor College of Medicine), Fuli Yu(Chinese Academy of Sciences), Huanming Yang, Lan-Yang Ch'ang, Wei Huang(Chinese Academy of Sciences), Bin Liu, Yan Shen(University of Hong Kong), Paul Kwong Hang Tam(University of Hong Kong), Lap-Chee Tsui(Chinese University of Hong Kong), Mary Miu Yee Waye(Hong Kong University of Science and Technology), J. Tze‐Fei Wong(Chinese Academy of Sciences), Changqing Zeng(Chinese Academy of Sciences), Qingrun Zhang(Illumina (United States)), Illumina(Illumina (United States)), Mark S. Chee(Illumina (United States)), Luana Galver(Illumina (United States)), Semyon Kruglyak(Illumina (United States)), Sarah S. Murray(McGill University), Arnold Oliphant(McGill University), Alexandre Montpetit(McGill University), Thomas J. Hudson(McGill University), Fanny Chagnon(McGill University), Vincent Ferretti(McGill University), Martin Leboeuf(Washington University in St. Louis), Michael Phillips(University of California, San Francisco), Andrei Verner(Washington University in St. Louis), Pui-Yan Kwok(Washington University in St. Louis), Shenghui Duan(Washington University in St. Louis), Denise L. Lind(Washington University in St. Louis), Raymond D. Miller(University of California, San Francisco), John P. Rice, Nancy L. Saccone, Patricia Taillon‐Miller, Ming Xiao, Yusuke Nakamura, Akihiro Sekine, Koki Sorimachi, Toshihiro Tanaka, Yoïchi Tanaka(Beijing Normal University), Tatsuhiko Tsunoda(Health Sciences University of Hokkaido), Eiji Yoshino(Shinshu University), David Bentley(University of Tsukuba), Panos Deloukas(University of Tsukuba), Sarah Hunt(Howard University), Don Powell(University of Ibadan), David Altshuler(University of Ibadan), Stacey B. Gabriel(Case Western Reserve University), Houcan Zhang(University of Ibadan), Changqing Zeng(University of Ibadan), Ichiro Matsuda(Howard University), Yoshimitsu Fukushima(University of Utah), Darryl Macer(University of Utah), Eiko Suda, Charles N. Rotimi, Clement Adebamowo, Toyin Aniagwu(Johns Hopkins University), Patricia A. Marshall(Johns Hopkins University), Olayemi Matthew(Johns Hopkins University), Chibuzor Nkwodimmah(University of Oxford), Charmaine D. M. Royal(University of Oxford), Mark Leppert(University of Oxford), Missy Dixon(University of Oxford), Lincoln D. Stein(University of Oxford), Fiona Cunningham(University of Oxford), Ardavan Kanani(North Carolina State University), Guðmundur Á. Þórisson(National Institutes of Health), Aravinda Chakravarti(National Institutes of Health), Peter E. Chen(Massachusetts Institute of Technology), David J. Cutler(Chinese Academy of Social Sciences), Carl Kashuk, Peter Donnelly(Howard University), Jonathan Marchini(Kyoto University), Gil McVean(Nagasaki University), Simon Myers(Wellcome Trust), Lon R. Cardon(Baylor College of Medicine), Gonçalo R. Abecasis(Baylor College of Medicine), Andrew P. Morris(Baylor College of Medicine), Bruce S. Weir(Washington University in St. Louis), James C. Mullikin(Washington University in St. Louis), Stephen T. Sherry, Michael Feolo(Massachusetts Institute of Technology), David Altshuler(Chinese Academy of Sciences), Mark Daly, Stephen F. Schaffner, Ren-Zong Qiu(McGill University), Genetic Interest Group, Alastair Kent, Georgia M. Dunston, Kazuto Kato, Norio Niikawa, Bartha Maria Knoppers, Morris W. Foster(National Institutes of Health), Ellen Wright Clayton(National Institutes of Health), Vivian Ota Wang(National Institutes of Health), Wellcome Trust(National Institutes of Health), Jessica Watkin, Richard A. Gibbs(National Institutes of Health), John W. Belmont(National Institutes of Health), Erica Sodergren(University of Maryland, Baltimore), George M. Weinstock(National Institutes of Health), Richard K. Wilson(Wellcome Trust), Lucinda Fulton(Wellcome Trust), Jane Rogers(Wellcome Trust), Susan J. Birren, Hua Han(Wellcome Trust), Chinese Ministry of Science and Technology(Wellcome Trust), Hongguang Wang(Johns Hopkins University), Genome Canada(Vanderbilt University), Martin Godbout(University of Utah), John C. Wallenburg(Johns Hopkins University), Génome Québec(Stanford University), Paul L'Archevêque(New York University), Guy Bellemare(University of Oklahoma), Japanese Ministry of Education, Culture, Sports, Science and Technology(University of New Mexico), Kazuo Todani(Université de Montréal), Takashi Fujita(University of California, San Francisco), Satoshi Tanaka(University of California, Los Angeles), Arthur L. Holden(University of Michigan), Eric Lai(University of Wisconsin–Madison), Francis S. Collins(Vanderbilt University), Lisa D. Brooks(Howard University), Jean E. McEwen(Wellcome Trust), Mark S. Guyer(Genetic Alliance), Elke Jordan(Massachusetts Institute of Technology), Jane L. Peterson(GlaxoSmithKline (United Kingdom)), Jack Spiegel(University of Washington), Lawrence M. Sung(University of Michigan), Lynn F. Zacharia(Harvard University Press), Wellcome Trust(University of Michigan), Karen Kennedy, Michael Dunn(University of Michigan), Richard Seabrook(Massachusetts Institute of Technology), Mark Shillito(University of Chicago), Barbara Skene(McGill University), John Stewart(Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa), Initial Planning Groups: Populations and Ethical, Legal and Social Issues Group(The University of Tokyo), David Valle(National Institutes of Health), Ellen Wright Clayton(Massachusetts Institute of Technology), Lynn B. Jorde(National Institutes of Health), John W. Belmont, Aravinda Chakravarti, Mildred K. Cho, Troy Duster, Morris W. Foster, Marla Jasperse, Bartha Maria Knoppers, Pui-Yan Kwok, Júlio Licinio, Jeffrey C. Long, Patricia A. Marshall, Pilar N. Ossorio, Vivian Ota Wang, Charles N. Rotimi, Charmaine D M Royal, Patricia Spallone, Sharon F. Terry, Methods Group, Eric S. Lander, Eric Lai, Deborah A. Nickerson, Gonçalo R. Abecasis, David Altshuler, David Bentley, Michael Boehnke, Lon R. Cardon, Mark Daly, Panos Deloukas, Julie A. Douglas, Stacey B. Gabriel, Richard R. Hudson, Thomas J. Hudson, Leonid Kruglyak, Pui-Yan Kwok, Yusuke Nakamura, Robert L. Nussbaum, Charmaine D. M. Royal, Stephen F. Schaffner, Stephen T. Sherry, Lincoln D. Stein, Toshihiro Tanaka
Cited by 6,164Open Access
Abstract
The goal of the International HapMap Project is to determine the common patterns of DNA sequence variation in the human genome and to make this information freely available in the public domain. An international consortium is developing a map of these patterns across the genome by determining the genotypes of one million or more sequence variants, their frequencies and the degree of association between them, in DNA samples from populations with ancestry from parts of Africa, Asia and Europe. The HapMap will allow the discovery of sequence variants that affect common disease, will facilitate development of diagnostic tools, and will enhance our ability to choose targets for therapeutic intervention.
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