Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure
Johan W. Smit(University of Groningen), Alfred H. Schinkel(Oncode Institute), Hugh Wiltshire(Roche (United Kingdom)), Maarten T. Huisman, Olaf van Tellingen(Dutch Cancer Society)
Cited by 355
Related Papers
Overcoming the blood–brain tumor barrier for effective glioblastoma treatment
|Drug Resistance Updates|2015|1k
Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins
|Proceedings of the National Academy of Sciences|1997|941
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine
|Proceedings of the National Academy of Sciences|1997|884