Renal phosphate handling: Physiology

Narayan Prasad(Sanjay Gandhi Post Graduate Institute of Medical Sciences), Dharmendra Bhadauria(Sanjay Gandhi Post Graduate Institute of Medical Sciences)
Indian Journal of Endocrinology and Metabolism
January 1, 2013
10.4103/2230-8210.113752
Cited by 59Open Access
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Abstract

Phosphorus is a common anion. It plays an important role in energy generation. Renal phosphate handling is regulated by three organs parathyroid, kidney and bone through feedback loops. These counter regulatory loops also regulate intestinal absorption and thus maintain serum phosphorus concentration in physiologic range. The parathyroid hormone, vitamin D, Fibrogenic growth factor 23 (FGF23) and klotho coreceptor are the key regulators of phosphorus balance in body.

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