Sex and Handedness Differences in Cerebral Blood Flow During Rest and Cognitive Activity
Ruben C. Gur(University of Pennsylvania), Raquel E. Gur(University of Pennsylvania), Walter D. Obrist(University of Pennsylvania), Jean Pierre Hungerbühler(University of Pennsylvania), Donald Younkin(University of Pennsylvania), Anna D. Rosen(University of Pennsylvania), Brett E. Skolnick(University of Pennsylvania), Martin Reivich(University of Pennsylvania)
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Abstract
Cognitive activity resulted in increased flow of blood to the cerebral hemispheres. The increase was greater to the left hemisphere for a verbal task and greater to the right hemisphere for a spatial task. The direction and degree of hemispheric flow asymmetry were influenced by sex and handedness, females having a higher rate of blood flow per unit weight of brain, and females and left-handers having a greater percentage of fast-clearing tissue, presumably gray matter.
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