A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

Nancy A. Thornberry; Herbert G. Bull; Jimmy Calaycay; Kevin T. Chapman; Andrew Howard; Matthew J. Kostura; Douglas K. Miller; Susan M. Molineaux; Jeffrey R. Weidner; John Auniņš; Keith Elliston; Julia M. Ayala; Francesca J. Casano; Jayne Chin; G J Ding; Linda A. Egger; Erin P. Gaffney; G Limjuco; Oksana Palyha; S Raju; Anna Rolando; J. Paul Salley; Ting-Ting Yamin; Terry D. Lee; John E. Shively; Malcolm MacCross; Richard A. Mumford; John A. Schmidt; Michael J. Tocci

doi:10.1038/356768a0

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

Nancy A. Thornberry(Merck & Co., Inc., Rahway, NJ, USA (United States)), Herbert G. Bull(Merck & Co., Inc., Rahway, NJ, USA (United States)), Jimmy Calaycay(Merck & Co., Inc., Rahway, NJ, USA (United States)), Kevin T. Chapman(Merck & Co., Inc., Rahway, NJ, USA (United States)), Andrew Howard(Merck & Co., Inc., Rahway, NJ, USA (United States)), Matthew J. Kostura(Merck & Co., Inc., Rahway, NJ, USA (United States)), Douglas K. Miller(Merck & Co., Inc., Rahway, NJ, USA (United States)), Susan M. Molineaux(Merck & Co., Inc., Rahway, NJ, USA (United States)), Jeffrey R. Weidner(Merck & Co., Inc., Rahway, NJ, USA (United States)), John Auniņš(Merck & Co., Inc., Rahway, NJ, USA (United States)), Keith Elliston(Merck & Co., Inc., Rahway, NJ, USA (United States)), Julia M. Ayala(Merck & Co., Inc., Rahway, NJ, USA (United States)), Francesca J. Casano(Merck & Co., Inc., Rahway, NJ, USA (United States)), Jayne Chin(Merck & Co., Inc., Rahway, NJ, USA (United States)), G J Ding(Merck & Co., Inc., Rahway, NJ, USA (United States)), Linda A. Egger(Merck & Co., Inc., Rahway, NJ, USA (United States)), Erin P. Gaffney(Merck & Co., Inc., Rahway, NJ, USA (United States)), G Limjuco(Merck & Co., Inc., Rahway, NJ, USA (United States)), Oksana Palyha(Merck & Co., Inc., Rahway, NJ, USA (United States)), S Raju(Merck & Co., Inc., Rahway, NJ, USA (United States)), Anna Rolando(Merck & Co., Inc., Rahway, NJ, USA (United States)), J. Paul Salley(Merck & Co., Inc., Rahway, NJ, USA (United States)), Ting-Ting Yamin(Merck & Co., Inc., Rahway, NJ, USA (United States)), Terry D. Lee(City of Hope), John E. Shively(Beckman Research Institute), Malcolm MacCross(Merck & Co., Inc., Rahway, NJ, USA (United States)), Richard A. Mumford(Merck & Co., Inc., Rahway, NJ, USA (United States)), John A. Schmidt(Merck & Co., Inc., Rahway, NJ, USA (United States)), Michael J. Tocci(Merck & Co., Inc., Rahway, NJ, USA (United States))

Nature

April 1, 1992

10.1038/356768a0

Cited by 2,573

Abstract

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