Enzyme‐Mediated Controlled Release Systems by Anchoring Peptide Sequences on Mesoporous Silica Supports

Carmen Coll(Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine), Laura Mondragón(Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine), Ramón Martínez‐Máñez(Universitat de València), Félix Sancenón(Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine), M. Dolores Marcos(Universitat Politècnica de València), Juán Soto(Universitat de València), Pedro Amorós(Universitat de València), Enríque Pérez‐Payá(Instituto de Biomedicina de Valencia)
Angewandte Chemie International Edition
February 1, 2011
Cited by 209Open Access
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Abstract

Gated community: Peptides anchored to the surface of silica mesoporous supports by a valid procedure act as gatekeepers. In this way, “zero release” supports that selectively deliver the cargo in the presence of a suitable peptidase are obtained (see picture, red spheres: cargo, colored chains: peptides).


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