Presenilin clinical mutations can affect γ‐secretase activity by different mechanisms
Mostafa Bentahir(Vlaams Instituut voor Biotechnologie), Bart De Strooper(UK Dementia Research Institute)
Cited by 410
Related Papers
Alteration of the microRNA network during the progression of Alzheimer's disease
|EMBO Molecular Medicine|2013|476
Presenilins and -Secretase: Structure, Function, and Role in Alzheimer Disease
|Cold Spring Harbor Perspectives in Medicine|2011|461
Phenotypic and Biochemical Analyses of BACE1- and BACE2-deficient Mice
|Journal of Biological Chemistry|2005|352
Contribution of Presenilin Transmembrane Domains 6 and 7 to a Water-containing Cavity in the γ-Secretase Complex
|Journal of Biological Chemistry|2006|135
Potential human transmission of amyloid β pathology: surveillance and risks
|The Lancet Neurology|2020|70