Integrating Oxaliplatin with Highly Luminescent Carbon Dots: An Unprecedented Theranostic Agent for Personalized Medicine

Min Zheng(Chinese Academy of Sciences), Shi Liu(Chinese Academy of Sciences), Jing Li(Chinese Academy of Sciences), Dan Qu(Chinese Academy of Sciences), Haifeng Zhao(Changchun Institute of Optics, Fine Mechanics and Physics), Xingang Guan(State Key Laboratory of Polymer Physics and Chemistry), Xiuli Hu(Changchun Institute of Applied Chemistry), Zhigang Xie(Changchun Institute of Applied Chemistry), Xiabin Jing(Changchun Institute of Applied Chemistry), Zaicheng Sun(Changchun Institute of Optics, Fine Mechanics and Physics)
Advanced Materials
March 14, 2014
Cited by 582

Abstract

A theranostic nanomedicine (CD-Oxa) is synthesized by means of the condensation reaction between the amino groups on the surface of fluorescent carbon dots (CDs) and the carboxyl group of the oxaliplatin derivative Oxa(IV)-COOH. CD-Oxa, which integrates the optical properties of CDs and the anticancer function of oxaliplatin, could be used for simultaneous drug delivery and fluorescent tracking. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.


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