In-vivo Characterization of Her-2/neu carcinogenesis in Mice Using Fluorescence Molecular Tomography
Helen A. Shih(Harvard University), Stephen D. Windsor(Harvard University), Ralph Weissleder(Harvard University), Vasilis Ntziachristos(Harvard University)
Cited by 6
Abstract
We reconstruct different bio-markers in Her-2/neu mice using Fluorescence Molecular Tomography (FMT) and appropriate fluorescent probe strategies. Protease up-regulation can serve as a generic detection marker whereas more specific antibody based imaging can be employed for higher specificity and more sensitive detection.
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