Carbon Dots for Multiphoton Bioimaging

Li Cao(Clemson University), Xin Wang(Clemson University), Mohammed J. Meziani(Clemson University), Fushen Lu(Clemson University), Haifang Wang(Clemson University), Pengju G. Luo(Clemson University), Yi Lin(Clemson University), Barbara A. Harruff(Clemson University), L. Monica Veca(Clemson University), Davoy Murray(Clemson University), Su‐Yuan Xie(Clemson University), Ya‐Ping Sun(Clemson University)
Journal of the American Chemical Society
August 28, 2007
Cited by 2,183Open Access
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Abstract

Carbon nanoparticles upon simple surface passivation exhibit bright photoluminescence. Reported here is a new finding that these carbon dots are also strongly two-photon luminescent with pulsed laser excitation in the near-infrared. The experimentally measured two-photon absorption cross-sections are comparable to those of the high-performance semiconductor quantum dots already available in the literature. The two-photon luminescence microscopy imaging of human breast cancer cells with internalized carbon dots is demonstrated.


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