Peptide-based activity-based probes (ABPs) for target-specific profiling of proteintyrosine phosphatases (PTPs)
Karunakaran Kalesh(National University of Singapore), Lay Pheng Tan(National University of Singapore), Kai Lü(National University of Singapore), Liqian Gao(National University of Singapore), Jigang Wang(National University of Singapore), Shao Q. Yao(National University of Singapore)
Cited by 55Open Access
Abstract
Synthesis of a novel unnatural amino acid (2-FMPT) for the solid-phase synthesis of peptide-based probes suitable for target-specific activity-based profiling of protein tyrosine phosphatases from crude proteomes is reported.
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