Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511
Mark H. Norman(Amgen (United States)), Paul E. Hughes(Amgen (United States)), Xiaochun Zhu(Amgen (United States)), Victor J. Cee(Amgen (United States)), Nuria Tamayo(Amgen (United States)), Markian M. Stec(Amgen (United States)), Adrian L. Smith(Amgen (United States)), Bin Wu(China Astronaut Research and Training Center), Raju Subramanian(Gilead Sciences (United States)), Noel D. D’Angelo(Amgen (United States)), Nancy R. Zhang(University of the Arts), Anthony B. Reed(Amgen (United States)), Nobuko Nishimura(Amgen (United States)), Kevin Yang(Revolution Medicines (United States)), Seifu Tadesse(Amgen (United States)), Brian A. Lanman(Harvard University), Leeanne Zalameda(Amgen (United States)), Tisha San Miguel(Amgen (United States)), Bradley J. Herberich(Amgen (United States)), Douglas A. Whittington(Amgen (United States)), Andrew S. Tasker(Amgen (United States)), Erin L. Mullady(Amgen (United States)), Claire Jackson(Babraham Institute), Liping H. Pettus(Amgen (United States)), Jian Jiang(Xuzhou Medical College), Shon K. Booker(Amgen (United States)), Longbin Liu(National University of Defense Technology), Divesh Aidasani(Amgen (United States)), Ling Wang(Guizhou University), Tian Wu(Guangzhou University of Chinese Medicine), Sean Caenepeel(Amgen (United States)), Kristin L. Andrews(Amgen (United States)), Yunxin Bo(Amgen (United States)), Daniel J. Freeman(Amgen (United States)), John D. McCarter(Amgen (United States)), Fang‐Tsao Hong(Amgen (United States)), Ryan P. Wurz(Amgen (United States))
Cited by 50
Related Papers
Integrin activation controls metastasis in human breast cancer
|Proceedings of the National Academy of Sciences|2001|580
Glucuronidation of Statins in Animals and Humans: A Novel Mechanism of Statin Lactonization
|Drug Metabolism and Disposition|2002|346
Effects of Fibrates on Metabolism of Statins in Human Hepatocytes
|Drug Metabolism and Disposition|2002|325
Chemistry and biology of natural and designed enediynes.
|Proceedings of the National Academy of Sciences|1993|255