The Use of Ampicillin in Acute Pancreatitis

Abstract

Letters1 December 1975The Use of Ampicillin in Acute PancreatitisROBERT M. CRAIG, M.D., ERL DORDAL, M.D., F.A.C.P., LEWIS MYLES, M.S., R.PH.ROBERT M. CRAIG, M.D.Search for more papers by this author, ERL DORDAL, M.D., F.A.C.P.Search for more papers by this author, LEWIS MYLES, M.S., R.PH.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-83-6-831 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe suggestion that bacteria may be involved pathophysiologically in acute pancreatitis has been supported by the efficacy of antibiotics in diminishing the mortality of experimental pancreatitis (1), and the possibly lower incidence of pancreatic abscesses since the use of antibiotics in pancreatitis (2). However, a recent retrospective review showed that the incidence of infectious complications in acute pancreatitis was similar in those given and not given prophylactic antibiotics (3). As there have been heretofore no published controlled studies, our investigation was designed to help answer this question, by comparing prophylactic ampicillin with placebo in the management of acute pancreatitis.All...References1. PERSKYSCHWEINBERGJACOB LFS: Aureomycin in experimental acute pancreatitis of dogs. Surgery 30:652-656, 1951 MedlineGoogle Scholar2. EVANS F: Pancreatic abscess. Am J Surg 117:537, 1969 CrossrefMedlineGoogle Scholar3. KODESCHDU PONT RH: Infectious complications of acute pancreatitis. Surg Gynecol Obstet 136:763-768, 1973 MedlineGoogle Scholar4. SWITZ D: Acute alcoholic pancreatitis: effect of clinical presentation and therapies on outcome at a V.A. Hospital (abstract). Ann Intern Med 78:816-817, 1973 LinkGoogle Scholar5. TRAPNELLRIGBYTALBOT JCC: A controlled trial of Trasylol in the treatment of acute pancreatitis. Br J Surg 61:177-182, 1974 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Veterans Administration Research Hospital; and Gastroenterology Department Northwestern University School of Medicine Chicago, Illinois 60611 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAntibiotic therapy in acute pancreatitis: From global overuse to evidence based recommendationsEarly management of acute pancreatitis: A review of the best evidenceJapanese guidelines for the management of acute pancreatitis: Japanese Guidelines 2015Is antibiotic prophylaxis beneficial in acute pancreatitis: first updateAntibiotic TherapyPancreatic InfectionAntibiotics in severe acute pancreatitisNutrition, Inflammation, and Acute PancreatitisInfectious Complications of Acute PancreatitisManagement of acute pancreatitis and complicationsAcute Pancreatitis: Should We Use Antibiotics?Systematic review and meta-analysis of antibiotic prophylaxis in severe acute pancreatitisAntibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitisFundamental and intensive care of acute pancreatitisThe Role of Antibiotics in the Management of Patients with Acute Necrotizing PancreatitisPancreatic InfectionSummarized Review of the Clinical Guideline of Acute Pancreatitis (Third Edition): Changes in the new assessment of severity and diagnostic criteriaPharmacotherapy for acute pancreatitisNecrotizing pancreatitis and antibiotic prophylaxis. 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GEOKAS, M.D.. Ph.D., HAROLD A. BALTAXE, M.D., PETER A. BANKS, M.D., JOSEPH SILVA Jr., M.D., CHARLES F. FREY, M.D.Controlled Clinical Trial of Peritoneal Lavage for the Treatment of Severe Acute PancreatitisResults of mobilization and drainage of the pancreas for acute pancreatitisAcute and chronic pancreatitisAllgemeine konservative TherapieIndikationen und Verfahrenswahl aus internistischer SichtCurrent Status of Diagnosis and Conservative Treatment of Acute PancreatitisIntensive medical treatment of severe acute pancreatitisInvited commentaryAkute und akut-rezidivierende PankreatitisSevere Acute PancreatitisEffect of pancreatitis on ampicillin excretion in pancreatic fluids of dogsAmpicillin Concentrations in Pancreatic Fluid Bile Obtained at Endoscopic Retrograde Cholangiopancreatography (ERCP)Treatment of Acute PancreatitisDrug Therapy of Acute PancreatitisPancreatitis: Pancreatic Pseudocysts and their Complications 1 December 1975Volume 83, Issue 6Page: 831-832KeywordsAbscessesAcute pancreatitisAntibioticsBacteriaMortalityPancreatitis Issue Published: 1 December 1975 PDF downloadLoading ...