Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer

Uddalak Bharadwaj(The University of Texas MD Anderson Cancer Center), David J. Tweardy(The University of Texas MD Anderson Cancer Center), Bhuvanesh Dave(University Hospital Galway), Judy C. Chang(Center for Human Genetics), Ammar Adam(Baylor College of Medicine), Moses M. Kasembeli(The University of Texas MD Anderson Cancer Center), David Torres(Baylor College of Medicine), Michael T. Lewis(Baylor College of Medicine), Wenjie Wei(Baylor College of Medicine), Lacey E. Dobrolecki(Baylor College of Medicine), Chad J. Creighton(Baylor College of Medicine), T. Kris Eckols(Baylor College of Medicine), Michael A. Mancini(Baylor College of Medicine), Melissa D. Landis(Baylor College of Medicine), Mikhail Kolosov(Baylor College of Medicine), X. Zhang(Baylor College of Medicine)
Oncogene
March 31, 2014
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