Photoinduced CO release, cellular uptake and cytotoxicity of a tris(pyrazolyl)methane (tpm) manganese tricarbonyl complex
Johanna Niesel(Ruhr University Bochum), António Pinto(Ruhr University Bochum), Harmel W. Peindy N’Dongo(Ruhr University Bochum), Klaus Merz(Ruhr University Bochum), Ingo Ott(Freie Universität Berlin), Ronald Gust(Freie Universität Berlin), Ulrich Schatzschneider(Ruhr University Bochum)
Cited by 266
Abstract
Cell viability studies of HT29 colon cancer cells treated with the CO-releasing compound [Mn(CO)(3)(tpm)]PF(6) revealed a significant photoinduced cytotoxicity comparable to that of established agent 5-fluorouracil (5-FU), while controls kept in the dark were unaffected at up to 100 microM.
Related Papers
No related papers found
Powered by citation graph analysis