Genetic studies of body mass index yield new insights for obesity biology

The LifeLines Cohort Study; Adam E. Locke; The AGEN-BMI Working Group; The GLGC; The ICBP; The MAGIC Investigators; Bratati Kahali; Sonja I. Berndt; Anne E. Justice; Tune H. Pers; Felix R. Day; C. E. Powell; Sailaja Vedantam; Martin L. Buchkovich; Jian Yang; Damien C. Croteau‐Chonka; Tõnu Esko; Tove Fall; Teresa Ferreira; Stefan Gustafsson; Zoltán Kutalik; Jian’an Luan; Reedik Mägi; Joshua C. Randall; Thomas W. Winkler; Andrew R. Wood; Tsegaselassie Workalemahu; Jessica D. Faul; Jennifer A. Smith; Wei Zhao; Wei Zhao; Jin Chen; Rudolf S.N. Fehrmann; Åsa K. Hedman; Juha Karjalainen; Ellen M. Schmidt; Devin Absher; Najaf Amin; Denise Anderson; Marian Beekman; Jennifer L. Bolton; Jennifer L. Bragg‐Gresham; Steven Buyske; Ayşe Demirkan; Guohong Deng; Georg Ehret; Bjarke Feenstra; Mary F. Feitosa; Krista Fischer; Anuj Goel; Jian Gong; Anne Jackson; Stavroula Kanoni; Marcus E. Kleber; Kati Kristiansson; Unhee Lim; Vaneet Lotay; Massimo Mangino; Irene Mateo Leach; Carolina Medina‐Gómez; Sarah E. Medland; Michael A. Nalls; Cameron D. Palmer; Dorota Pasko; Sonali Pechlivanis; Marjolein J. Peters; Inga Prokopenko; Dmitry Shungin; Alena Stančáková; Rona J. Strawbridge; Yun Ju Sung; Toshiko Tanaka; Alexander Teumer; Stella Trompet; Sander W. van der Laan; Jessica van Setten; Jana V. van Vliet‐Ostaptchouk; Zhaoming Wang; Loïc Yengo; Weihua Zhang; Aaron Isaacs; Eva Albrecht; Johan Ärnlöv; Gillian M. Arscott; Antony Attwood; Stefania Bandinelli; Amy Barrett; Isabelita Bas; Claire Bellis; Amanda J. Bennett; Christian Berne; Roza Blagieva; Matthias Blüher; Stefan Böhringer; Lori L. Bonnycastle; Yvonne Böttcher; Heather A. Boyd; Marcel Bruinenberg; Ida Henriette Caspersen; Yii‐Der Ida Chen; Robert Clarke; E. Warwick Daw; Anton J. M. de Craen; Graciela Delgado; Maria Dimitriou; Alex S. F. Doney; Niina Eklund; Karol Estrada; Elodie Eury; Lasse Folkersen; Ross M. Fraser; Melissa E. Garcia; Frank Geller; Vilmantas Giedraitis; Bruna Gigante; Alan S. Go; Alain Golay; Alison H. Goodall; Scott D. Gordon; Mathias Gorski; Hans J. Grabe; Harald Grallert; Tanja B. Grammer; Jürgen Gräßler; Henrik Grönberg; Christopher J. Groves; Gaëlle Gusto; Jeffrey Haessler; Per Hall; Toomas Haller; Göran Hallmans; Catharina A. Hartman; Maija Hassinen; Caroline Hayward; Nancy L. Heard‐Costa; Quinta Helmer; Christian Hengstenberg; Oddgeir L. Holmen; Jouke‐Jan Hottenga; Alan L. James; Janina M. Jeff; Åsa Johansson; Jennifer Jolley; Thorhildur Juliusdottir; Leena Kinnunen; Wolfgang Köenig; Markku Koskenvuo; Wolfgang Kratzer; Jaana Laitinen; Claudia Lamina; Karin Leander; Sang Lee; Peter Lichtner; Lars Lind; Jaana Lindström; Ken Sin Lo; Stéphane Lobbens; Roberto Lorbeer; Yingchang Lu; François Mach; Patrik K. E. Magnusson; Anubha Mahajan; Wendy L. McArdle; Stela McLachlan; Cristina Menni; Sigrun Merger; Evelin Mihailov; Lili Milani; Alireza Moayyeri; Keri L. Monda; Mario A. Morken; Antonella Mulas; Gabriele Müller; Martina Müller‐Nurasyid; Arthur W. Musk; Ramaiah Nagaraja; Markus M. Nöthen; Ilja M. Nolte; Stefan Pilz; Nigel W. Rayner; Frida Renström; Rainer Rettig; Janina S. Ried; Stephan Ripke; Neil R. Robertson; Lynda M. Rose; Serena Sanna; Hubert Scharnagl; Salome Scholtens; Fredrick R. Schumacher; William R. Scott; Thomas Seufferlein; Jianxin Shi; Albert V. Smith; Joanna Smolonska; Alice Stanton; Valgerður Steinthórsdóttir; Kathleen Stirrups; Heather M. Stringham; Johan Sundström; Morris A. Swertz; Amy J. Swift; Ann‐Christine Syvänen; Sian-Tsung Tan; Bamidele O. Tayo; Barbara Thorand; Guðmar Þorleifsson; Jonathan P. Tyrer; Hae‐Won Uh; Liesbeth Vandenput; Frank C. Verhulst; Sita H. Vermeulen; Niek Verweij; Judith M. Vonk; Lindsay L. Waite; Helen R. Warren; Dawn Waterworth; Michael N. Weedon; Lynne R. Wilkens; Christina Willenborg; Tom Wilsgaard; Mary K. Wojczynski; Andrew Wong; Alan F. Wright; Qunyuan Zhang; Eoin Brennan; Murim Choi; Zari Dastani; Alexander Drong; Per Eriksson; Anders Franco-Cereceda; Jesper R. Gådin; Ali G. Gharavi; Michael E. Goddard; Robert E. Handsaker; Jinyan Huang; Fredrik Karpe; Sekar Kathiresan; Sarah Keildson; Krzysztof Kiryluk; Michiaki Kubo; Jong‐Young Lee; Liming Liang; Richard P. Lifton; Baoshan Ma; Steven A. McCarroll; Amy Jayne McKnight; Josine L. Min; Miriam F. Moffatt; Grant W. Montgomery; Joanne M. Murabito; George Nicholson; Dale R. Nyholt; Yukinori Okada; John R. B. Perry; Rajkumar Dorajoo; Eva Reinmaa; Rany M. Salem; Niina Sandholm; Robert A. Scott; Lisette Stolk; Atsushi Takahashi; Toshihiro Tanaka; Ferdinand M. van’t Hooft; Anna A. E. Vinkhuyzen; Harm-Jan Westra; Wei Zheng; Krina T. Zondervan; Andrew C. Heath; Dominique Arveiler; Stephan J. L. Bakker; John Beilby; Richard N. Bergman; John Blangero; Pascal Bovet; Harry Campbell; Mark J. Caulfield; Giancarlo Cesana; Aravinda Chakravarti; Daniel I. Chasman; Peter S. Chines; Francis S. Collins; Dana C. Crawford; L. Adrienne Cupples; Daniele Cusi; John Danesh; Ulf dé Fairé; Hester M. den Ruijter; Anna F. Dominiczak; Raimund Erbel; Jeanette Erdmann; Johan G. Eriksson; Martin Farrall; Stephan B. Felix; Ele Ferrannini; Jean Ferrières; Ian Ford; Nita G. Forouhi; Terrence Forrester; Oscar H. Franco; Ron T. Gansevoort; Pablo V. Gejman; Christian Gieger; Omri Gottesman; Vilmundur Guðnason; Ulf Gyllensten; Alistair S. Hall; Tamara B. Harris; Andrew T. Hattersley; Andrew A. Hicks; Lucia A. Hindorff; Aroon D. Hingorani; Albert Hofman; Georg Homuth; G. Kees Hovingh; Steve E. Humphries; Steven C. Hunt; Elina Hyppönen; Thomas Illig; Kevin B. Jacobs; Marjo‐Riitta Järvelin; Karl‐Heinz Jöckel; Berit Johansen; Pekka Jousilahti; J. Wouter Jukema; Antti Jula; Jaakko Kaprio; John J.P. Kastelein; Sirkka Keinänen‐Kiukaanniemi; Lambertus A. Kiemeney; Paul Knekt; Jaspal S. Kooner; Charles Kooperberg; Péter Kovács; Aldi T. Kraja; Meena Kumari; Johanna Kuusisto; Timo A. Lakka; Claudia Langenberg; Loı̈c Le Marchand; Terho Lehtimäki; Valeriya Lyssenko; Satu Männistö; André Marette; Tara C. Matise; Colin A. McKenzie; Barbara McKnight; Frans L. Moll; Andrew D. Morris; Andrew P. Morris; Jeffrey C. Murray; Mari Nelis; Claes Ohlsson; Albertine J. Oldehinkel; Ken K. Ong; Pamela A. F. Madden; Gerard Pasterkamp; John F. Peden; Annette Peters; Dirkje S. Postma; Peter P. Pramstaller; Jackie F. Price; Lu Qi; Olli Raitakari; Tuomo Rankinen; D. C. Rao; Treva Rice; Paul M. Ridker; John D. Rioux; Marylyn D. Ritchie; Igor Rudan; Veikko Salomaa; Nilesh J. Samani; Jouko Saramies; Mark A. Sarzynski; Heribert Schunkert; Peter Schwarz; Peter Sever; Alan R. Shuldiner; Juha Sinisalo; Ronald P. Stolk; Konstantin Strauch; Anke Tönjes; David‐Alexandre Trégouët; Angelo Tremblay; Elena Tremoli; Jarmo Virtamo; Marie‐Claude Vohl; Uwe Völker; Gérard Waeber; Gonneke Willemsen; Jacqueline C.M. Witteman; M. Carola Zillikens; Linda S. Adair; Philippe Amouyel; Folkert W. Asselbergs; Themistocles L. Assimes; Murielle Bochud; Bernhard O. Boehm; Eric Boerwinkle; Stefan R. Bornstein; Erwin P. Böttinger; Claude Bouchard; Stéphane Cauchi; John C. Chambers; Stephen J. Chanock; Richard S. Cooper; Paul I. W. de Bakker; George Dedoussis; Luigi Ferrucci; Paul W. Franks; Philippe Froguel; Leif C. Groop; Christopher A. Haiman; Anders Hamsten; Jennie Hui; David J. Hunter; Kristian Hveem; Robert C. Kaplan; Mika Kivimäki; Diana Kuh; Markku Laakso; Ching‐Ti Liu; Nicholas G. Martin; Winfried März; Mads Melbye; Andres Metspalu; Susanne Moebus; Patricia B. Munroe; Inger Njølstad; Ben A. Oostra; Colin N. A. Palmer; Nancy L. Pedersen; Markus Perola; Louis Përusse; Ulrike Peters; Chris Power; Thomas Quertermous; Rainer Rauramaa; Fernando Rivadeneira; Timo Saaristo; Danish Saleheen; Naveed Sattar; Eric E. Schadt; David Schlessinger; P. Eline Slagboom; Harold Snieder; Tim D. Spector; Unnur Þorsteinsdóttir; Michael Stümvoll; Jaakko Tuomilehto; André G. Uitterlinden; Matti Uusitupa; Pim van der Harst; Mark Walker; Henri Wallaschofski; Nicholas J. Wareham; Hugh Watkins; David R. Weir; H‐Erich Wichmann; James F. Wilson; Pieter Zanen; Ingrid B. Borecki; Panos Deloukas; Caroline S. Fox; Iris M. Heid; Jeffrey R. O’Connell; David P. Strachan; Kāri Stefánsson; Cornelia M. van Duijn; Gonçalo R. Abecasis; Lude Franke; Timothy M. Frayling; Mark I. McCarthy; Peter M. Visscher; André Scherag; Cristen J. Willer; Michael Boehnke; Karen L. Mohlke; Cecilia M. Lindgren; J. Beckmann; Inês Barroso; Kari E. North; Erik Ingelsson; Joel N. Hirschhorn; Ruth J. F. Loos; Elizabeth K. Speliotes

doi:10.1038/nature14177

Genetic studies of body mass index yield new insights for obesity biology

The LifeLines Cohort Study(University of Michigan), Adam E. Locke(University of Michigan), The AGEN-BMI Working Group(National Institutes of Health), The GLGC(University of North Carolina at Chapel Hill), The ICBP(Broad Institute), The MAGIC Investigators(University of Cambridge), Bratati Kahali(University of Michigan), Sonja I. Berndt(Broad Institute), Anne E. Justice(University of North Carolina at Chapel Hill), Tune H. Pers(Broad Institute), Felix R. Day(University of North Carolina at Chapel Hill), C. E. Powell(Broad Institute), Sailaja Vedantam(Broad Institute), Martin L. Buchkovich(University of North Carolina at Chapel Hill), Jian Yang(Uppsala University), Damien C. Croteau‐Chonka(University of North Carolina at Chapel Hill), Tõnu Esko(Broad Institute), Tove Fall(Uppsala University), Teresa Ferreira(Centre for Human Genetics), Stefan Gustafsson(Uppsala University), Zoltán Kutalik(SIB Swiss Institute of Bioinformatics), Jian’an Luan(Harvard University), Reedik Mägi(Centre for Human Genetics), Joshua C. Randall(Centre for Human Genetics), Thomas W. Winkler(University of Cambridge), Andrew R. Wood(University of Exeter), Tsegaselassie Workalemahu(Harvard University), Jessica D. Faul(University Medical Center Groningen), Jennifer A. Smith(Uppsala University), Wei Zhao(University Medical Center Groningen), Wei Zhao(University of Michigan), Jin Chen(University of Michigan), Rudolf S.N. Fehrmann(University Medical Center Groningen), Åsa K. Hedman(Uppsala University), Juha Karjalainen(University Medical Center Groningen), Ellen M. Schmidt(University of Michigan), Devin Absher(University of Michigan), Najaf Amin(Rutgers, The State University of New Jersey), Denise Anderson(The Kids Research Institute Australia), Marian Beekman(Army Medical University), Jennifer L. Bolton(Johns Hopkins University), Jennifer L. Bragg‐Gresham(Statens Serum Institut), Steven Buyske(Rutgers, The State University of New Jersey), Ayşe Demirkan(Leiden University Medical Center), Guohong Deng(Centre for Human Genetics), Georg Ehret(Johns Hopkins University), Bjarke Feenstra(Statens Serum Institut), Mary F. Feitosa(Queen Mary University of London), Krista Fischer(Heidelberg University), Anuj Goel(Centre for Human Genetics), Jian Gong(University of Hawaiʻi at Mānoa), Anne Jackson(University of Michigan), Stavroula Kanoni(Queen Mary University of London), Marcus E. Kleber(University Medical Center Groningen), Kati Kristiansson(Erasmus MC), Unhee Lim(QIMR Berghofer Medical Research Institute), Vaneet Lotay(National Institutes of Health), Massimo Mangino(Broad Institute), Irene Mateo Leach(University Medical Center Groningen), Carolina Medina‐Gómez(Erasmus MC), Sarah E. Medland(QIMR Berghofer Medical Research Institute), Michael A. Nalls(National Institutes of Health), Cameron D. Palmer(Broad Institute), Dorota Pasko(University of Eastern Finland), Sonali Pechlivanis(Karolinska Institutet), Marjolein J. Peters(Washington University in St. Louis), Inga Prokopenko(Centre for Human Genetics), Dmitry Shungin(Lund University), Alena Stančáková(University of Eastern Finland), Rona J. Strawbridge(Karolinska Institutet), Yun Ju Sung(Washington University in St. Louis), Toshiko Tanaka(Tokyo Medical and Dental University), Alexander Teumer(National Institutes of Health), Stella Trompet(Centre National de la Recherche Scientifique), Sander W. van der Laan(Ealing Hospital), Jessica van Setten(Erasmus MC), Jana V. van Vliet‐Ostaptchouk(University Medical Center Groningen), Zhaoming Wang(Uppsala University), Loïc Yengo(Centre National de la Recherche Scientifique), Weihua Zhang(NHS Blood and Transplant), Aaron Isaacs(Leiden University Medical Center), Eva Albrecht(Helmholtz Zentrum München), Johan Ärnlöv(Dalarna University), Gillian M. Arscott(Texas Biomedical Research Institute), Antony Attwood(NHS Blood and Transplant), Stefania Bandinelli(Uppsala University), Amy Barrett(Universität Ulm), Isabelita Bas(IFB Adiposity Diseases), Claire Bellis(Texas Biomedical Research Institute), Amanda J. Bennett(University of Oxford), Christian Berne(Uppsala University), Roza Blagieva(Statens Serum Institut), Matthias Blüher(University Medical Center Groningen), Stefan Böhringer(Norwegian University of Science and Technology), Lori L. Bonnycastle(University of California, Los Angeles), Yvonne Böttcher(University of Oxford), Heather A. Boyd(Statens Serum Institut), Marcel Bruinenberg(University Medical Center Groningen), Ida Henriette Caspersen(Norwegian University of Science and Technology), Yii‐Der Ida Chen(Harokopio University of Athens), Robert Clarke(University of Dundee), E. Warwick Daw(Washington University in St. Louis), Anton J. M. de Craen(Broad Institute), Graciela Delgado(Centre National de la Recherche Scientifique), Maria Dimitriou(Karolinska Institutet), Alex S. F. Doney(University of Dundee), Niina Eklund(Finnish Institute for Health and Welfare), Karol Estrada(Statens Serum Institut), Elodie Eury(Uppsala University), Lasse Folkersen(Karolinska Institutet), Ross M. Fraser(Kaiser Permanente), Melissa E. Garcia(University Hospital of Geneva), Frank Geller(Statens Serum Institut), Vilmantas Giedraitis(Uppsala University), Bruna Gigante(Karolinska Institutet), Alan S. Go(Kaiser Permanente), Alain Golay(Helmholtz Zentrum München), Alison H. Goodall(University of Leicester), Scott D. Gordon(QIMR Berghofer Medical Research Institute), Mathias Gorski(Karolinska Institutet), Hans J. Grabe(Universitätsmedizin Greifswald), Harald Grallert(Helmholtz Zentrum München), Tanja B. Grammer(Heidelberg University), Jürgen Gräßler(Karolinska Institutet), Henrik Grönberg(Karolinska Institutet), Christopher J. Groves(University of Oxford), Gaëlle Gusto(University Medical Center Groningen), Jeffrey Haessler(University of Eastern Finland), Per Hall(Western General Hospital), Toomas Haller(Boston University), Göran Hallmans(Leiden University Medical Center), Catharina A. Hartman(University Medical Center Groningen), Maija Hassinen(University of Eastern Finland), Caroline Hayward(Western General Hospital), Nancy L. Heard‐Costa(Boston University), Quinta Helmer(Leiden University Medical Center), Christian Hengstenberg(Uppsala University), Oddgeir L. Holmen(NHS Blood and Transplant), Jouke‐Jan Hottenga(Centre for Human Genetics), Alan L. James(The University of Western Australia), Janina M. Jeff(Universität Ulm), Åsa Johansson(Uppsala University), Jennifer Jolley(NHS Blood and Transplant), Thorhildur Juliusdottir(Centre for Human Genetics), Leena Kinnunen(Innsbruck Medical University), Wolfgang Köenig(Universität Ulm), Markku Koskenvuo(University of Helsinki), Wolfgang Kratzer(Universität Ulm), Jaana Laitinen(Uppsala University), Claudia Lamina(Innsbruck Medical University), Karin Leander(Montreal Heart Institute), Sang Lee(Centre National de la Recherche Scientifique), Peter Lichtner(Universitätsmedizin Greifswald), Lars Lind(Uppsala University), Jaana Lindström(Finnish Institute for Health and Welfare), Ken Sin Lo(Montreal Heart Institute), Stéphane Lobbens(Centre National de la Recherche Scientifique), Roberto Lorbeer(Universitätsmedizin Greifswald), Yingchang Lu(Child Health and Development Institute), François Mach(King's College London), Patrik K. E. Magnusson(Universität Ulm), Anubha Mahajan(Centre for Human Genetics), Wendy L. McArdle(University of Bristol), Stela McLachlan(King's College London), Cristina Menni(University of North Carolina at Chapel Hill), Sigrun Merger(Universität Ulm), Evelin Mihailov(Institute of Genetic and Biomedical Research), Lili Milani(University Hospital Carl Gustav Carus), Alireza Moayyeri(King's College London), Keri L. Monda(University of North Carolina at Chapel Hill), Mario A. Morken(National Human Genome Research Institute), Antonella Mulas(University of Bonn), Gabriele Müller(University Medical Center Groningen), Martina Müller‐Nurasyid(Zimmer Biomet (Netherlands)), Arthur W. Musk(Centre for Human Genetics), Ramaiah Nagaraja(Lund University), Markus M. Nöthen(University of Bonn), Ilja M. Nolte(University Medical Center Groningen), Stefan Pilz(Harvard University), Nigel W. Rayner(Centre for Human Genetics), Frida Renström(Brigham and Women's Hospital), Rainer Rettig(Universitätsmedizin Greifswald), Janina S. Ried(Medical University of Graz), Stephan Ripke(Broad Institute), Neil R. Robertson(University of Southern California), Lynda M. Rose(Brigham and Women's Hospital), Serena Sanna(Universität Ulm), Hubert Scharnagl(Medical University of Graz), Salome Scholtens(University Medical Center Groningen), Fredrick R. Schumacher(University of Southern California), William R. Scott(Royal College of Surgeons in Ireland), Thomas Seufferlein(deCODE Genetics (Iceland)), Jianxin Shi(Queen Mary University of London), Albert V. Smith(University of Iceland), Joanna Smolonska(Uppsala University), Alice Stanton(University Medical Center Groningen), Valgerður Steinthórsdóttir(deCODE Genetics (Iceland)), Kathleen Stirrups(Uppsala University), Heather M. Stringham(University of Michigan), Johan Sundström(Uppsala University), Morris A. Swertz(University Medical Center Groningen), Amy J. Swift(deCODE Genetics (Iceland)), Ann‐Christine Syvänen(Uppsala University), Sian-Tsung Tan(Ealing Hospital), Bamidele O. Tayo(Loyola University Chicago), Barbara Thorand(Erasmus MC), Guðmar Þorleifsson(deCODE Genetics (Iceland)), Jonathan P. Tyrer(University Medical Center Groningen), Hae‐Won Uh(University Medical Center Groningen), Liesbeth Vandenput(HudsonAlpha Institute for Biotechnology), Frank C. Verhulst(Queen Mary University of London), Sita H. Vermeulen(Radboud University Nijmegen), Niek Verweij(University Medical Center Groningen), Judith M. Vonk(University of Hawaiʻi at Mānoa), Lindsay L. Waite(Institute for Integrative and Experimental Genomics), Helen R. Warren(Queen Mary University of London), Dawn Waterworth(GlaxoSmithKline (United Kingdom)), Michael N. Weedon(University of Exeter), Lynne R. Wilkens(Western General Hospital), Christina Willenborg(Washington University in St. Louis), Tom Wilsgaard(University College Dublin), Mary K. Wojczynski(Seoul National University), Andrew Wong(MRC Unit for Lifelong Health and Ageing), Alan F. Wright(Centre for Human Genetics), Qunyuan Zhang(Washington University in St. Louis), Eoin Brennan(University College Dublin), Murim Choi(Seoul National University), Zari Dastani(McGill University), Alexander Drong(Centre for Human Genetics), Per Eriksson(Broad Institute), Anders Franco-Cereceda(Harvard University), Jesper R. Gådin(Karolinska Institutet), Ali G. Gharavi(Harvard University), Michael E. Goddard(Centre for Human Genetics), Robert E. Handsaker(Broad Institute), Jinyan Huang(Harvard University), Fredrik Karpe(University of Oxford), Sekar Kathiresan(Broad Institute), Sarah Keildson(Centre for Human Genetics), Krzysztof Kiryluk(Harvard University), Michiaki Kubo(Broad Institute), Jong‐Young Lee(Queen's University Belfast), Liming Liang(Harvard University), Richard P. Lifton(Howard Hughes Medical Institute), Baoshan Ma(Harvard University), Steven A. McCarroll(Broad Institute), Amy Jayne McKnight(Queen's University Belfast), Josine L. Min(QIMR Berghofer Medical Research Institute), Miriam F. Moffatt(Tokyo Medical and Dental University), Grant W. Montgomery(King's College London), Joanne M. Murabito(Boston University), George Nicholson(University of Oxford), Dale R. Nyholt(Broad Institute), Yukinori Okada(Tokyo Medical and Dental University), John R. B. Perry(Centre for Human Genetics), Rajkumar Dorajoo(Agency for Science, Technology and Research), Eva Reinmaa(RIKEN Center for Integrative Medical Sciences), Rany M. Salem(Broad Institute), Niina Sandholm(Helsinki University Hospital), Robert A. Scott(The University of Queensland), Lisette Stolk(University Medical Center Groningen), Atsushi Takahashi(RIKEN Center for Integrative Medical Sciences), Toshihiro Tanaka(Tokyo Medical and Dental University), Ferdinand M. van’t Hooft(Washington University in St. Louis), Anna A. E. Vinkhuyzen(The University of Queensland), Harm-Jan Westra(University Medical Center Groningen), Wei Zheng(Pathwest Laboratory Medicine), Krina T. Zondervan(Cedars-Sinai Medical Center), Andrew C. Heath(Texas Biomedical Research Institute), Dominique Arveiler(University Hospital of Lausanne), Stephan J. L. Bakker(University Medical Center Groningen), John Beilby(Queen Mary University of London), Richard N. Bergman(Cedars-Sinai Medical Center), John Blangero(Texas Biomedical Research Institute), Pascal Bovet(Brigham and Women's Hospital), Harry Campbell(National Human Genome Research Institute), Mark J. Caulfield(Queen Mary University of London), Giancarlo Cesana(Vanderbilt University), Aravinda Chakravarti(Johns Hopkins University), Daniel I. Chasman(Brigham and Women's Hospital), Peter S. Chines(University of Cambridge), Francis S. Collins(Karolinska Institutet), Dana C. Crawford(Vanderbilt University), L. Adrienne Cupples(Boston University), Daniele Cusi(University of Milan), John Danesh(University of Cambridge), Ulf dé Fairé(Karolinska Institutet), Hester M. den Ruijter(University Medical Center Utrecht), Anna F. Dominiczak(Universitätsmedizin Greifswald), Raimund Erbel(University of Pisa), Jeanette Erdmann(Institute for Integrative and Experimental Genomics), Johan G. Eriksson(University of Helsinki), Martin Farrall(Centre for Human Genetics), Stephan B. Felix(Universitätsmedizin Greifswald), Ele Ferrannini(University of Pisa), Jean Ferrières(University Medical Center Groningen), Ian Ford(NorthShore University HealthSystem), Nita G. Forouhi(University of Cambridge), Terrence Forrester(University of the West Indies), Oscar H. Franco(University of Iceland), Ron T. Gansevoort(Uppsala University), Pablo V. Gejman(University of Leeds), Christian Gieger(Helmholtz Zentrum München), Omri Gottesman(University of Exeter), Vilmundur Guðnason(Eurac Research), Ulf Gyllensten(Uppsala University), Alistair S. Hall(University of Leeds), Tamara B. Harris(Erasmus MC), Andrew T. Hattersley(University of Exeter), Andrew A. Hicks(Eurac Research), Lucia A. Hindorff(National Human Genome Research Institute), Aroon D. Hingorani(University of Utah), Albert Hofman(University of South Australia), Georg Homuth(Universitätsmedizin Greifswald), G. Kees Hovingh(Amsterdam UMC Location University of Amsterdam), Steve E. Humphries(University College London), Steven C. Hunt(University of Utah), Elina Hyppönen(University of South Australia), Thomas Illig(Helmholtz Zentrum München), Kevin B. Jacobs(National Institutes of Health), Marjo‐Riitta Järvelin(Oulu University Hospital), Karl‐Heinz Jöckel(University of Helsinki), Berit Johansen(Norwegian University of Science and Technology), Pekka Jousilahti(Finnish Institute for Health and Welfare), J. Wouter Jukema(Radboud University Nijmegen), Antti Jula(Finnish Institute for Health and Welfare), Jaakko Kaprio(University of Helsinki), John J.P. Kastelein(Amsterdam UMC Location University of Amsterdam), Sirkka Keinänen‐Kiukaanniemi(Oulu University Hospital), Lambertus A. Kiemeney(Radboud University Nijmegen), Paul Knekt(University of Essex), Jaspal S. Kooner(Imperial College Healthcare NHS Trust), Charles Kooperberg(University of Eastern Finland), Péter Kovács(IFB Adiposity Diseases), Aldi T. Kraja(University of Hawaiʻi at Mānoa), Meena Kumari(University of Essex), Johanna Kuusisto(Steno Diabetes Centers), Timo A. Lakka(University of Eastern Finland), Claudia Langenberg(University of Cambridge), Loı̈c Le Marchand(Rutgers, The State University of New Jersey), Terho Lehtimäki(University of the West Indies), Valeriya Lyssenko(Steno Diabetes Centers), Satu Männistö(University Medical Center Utrecht), André Marette(University of Dundee), Tara C. Matise(Rutgers, The State University of New Jersey), Colin A. McKenzie(University of Iowa), Barbara McKnight(University of Washington), Frans L. Moll(University Medical Center Utrecht), Andrew D. Morris(University Medical Center Groningen), Andrew P. Morris(Centre for Human Genetics), Jeffrey C. Murray(University of Iowa), Mari Nelis(University Medical Center Utrecht), Claes Ohlsson(Illumina (United Kingdom)), Albertine J. Oldehinkel(University Medical Center Groningen), Ken K. Ong(University Medical Center Groningen), Pamela A. F. Madden(Eurac Research), Gerard Pasterkamp(University Medical Center Utrecht), John F. Peden(Harvard University), Annette Peters(University of Turku), Dirkje S. Postma(Pennington Biomedical Research Center), Peter P. Pramstaller(Eurac Research), Jackie F. Price(Washington University in St. Louis), Lu Qi(Brigham and Women's Hospital), Olli Raitakari(University of Turku), Tuomo Rankinen(Pennington Biomedical Research Center), D. C. Rao(Washington University in St. Louis), Treva Rice(Washington University in St. Louis), Paul M. Ridker(Brigham and Women's Hospital), John D. Rioux(Montreal Heart Institute), Marylyn D. Ritchie(Pennington Biomedical Research Center), Igor Rudan(German Centre for Cardiovascular Research), Veikko Salomaa(Finnish Institute for Health and Welfare), Nilesh J. Samani(University of Leicester), Jouko Saramies(University of Maryland, Baltimore), Mark A. Sarzynski(Pennington Biomedical Research Center), Heribert Schunkert(University Medical Center Groningen), Peter Schwarz(Zimmer Biomet (Netherlands)), Peter Sever(IFB Adiposity Diseases), Alan R. Shuldiner(University of Maryland, Baltimore), Juha Sinisalo(Helsinki University Hospital), Ronald P. Stolk(University Medical Center Groningen), Konstantin Strauch(Zimmer Biomet (Netherlands)), Anke Tönjes(IFB Adiposity Diseases), David‐Alexandre Trégouët(Inserm), Angelo Tremblay(Université Laval), Elena Tremoli(Centro Cardiologico Monzino), Jarmo Virtamo(Erasmus MC), Marie‐Claude Vohl(Erasmus MC), Uwe Völker(University of North Carolina at Chapel Hill), Gérard Waeber(Inserm), Gonneke Willemsen(Academic Center for Dentistry Amsterdam), Jacqueline C.M. Witteman(Erasmus MC), M. Carola Zillikens(Erasmus MC), Linda S. Adair(University of North Carolina at Chapel Hill), Philippe Amouyel(Inserm), Folkert W. Asselbergs(University Medical Center Utrecht), Themistocles L. Assimes(Stanford University), Murielle Bochud(Pennington Biomedical Research Center), Bernhard O. Boehm(Centre National de la Recherche Scientifique), Eric Boerwinkle(Imperial College Healthcare NHS Trust), Stefan R. Bornstein(National Institutes of Health), Erwin P. Böttinger(Loyola University Chicago), Claude Bouchard(Pennington Biomedical Research Center), Stéphane Cauchi(Centre National de la Recherche Scientifique), John C. Chambers(Imperial College Healthcare NHS Trust), Stephen J. Chanock(National Institutes of Health), Richard S. Cooper(Centre National de la Recherche Scientifique), Paul I. W. de Bakker(Brigham and Women's Hospital), George Dedoussis(University of Southern California), Luigi Ferrucci(Karolinska Institutet), Paul W. Franks(Harvard University), Philippe Froguel(Brigham and Women's Hospital), Leif C. Groop(Lund University), Christopher A. Haiman(University of Southern California), Anders Hamsten(Karolinska Institutet), Jennie Hui(The University of Western Australia), David J. Hunter(Brigham and Women's Hospital), Kristian Hveem(Norwegian University of Science and Technology), Robert C. Kaplan(Albert Einstein College of Medicine), Mika Kivimäki(Synlab Czech (Czechia)), Diana Kuh(MRC Unit for Lifelong Health and Ageing), Markku Laakso(University of Eastern Finland), Ching‐Ti Liu(Institut für Medizinische Informatik, Biometrie und Epidemiologie), Nicholas G. Martin(Queen Mary University of London), Winfried März(Synlab Czech (Czechia)), Mads Melbye(Erasmus MC), Andres Metspalu(University of Dundee), Susanne Moebus(Karolinska Institutet), Patricia B. Munroe(Queen Mary University of London), Inger Njølstad(Université Laval), Ben A. Oostra(Leiden University Medical Center), Colin N. A. Palmer(Broad Institute), Nancy L. Pedersen(Karolinska Institutet), Markus Perola(University of Eastern Finland), Louis Përusse(Erasmus MC), Ulrike Peters(Finnish Diabetes Association), Chris Power(University of Cambridge), Thomas Quertermous(University of Glasgow), Rainer Rauramaa(University of Eastern Finland), Fernando Rivadeneira(Erasmus MC), Timo Saaristo(Leiden University Medical Center), Danish Saleheen(University Medical Center Groningen), Naveed Sattar(King's College London), Eric E. Schadt(deCODE Genetics (Iceland)), David Schlessinger(IFB Adiposity Diseases), P. Eline Slagboom(Universität für Weiterbildung Krems), Harold Snieder(University Medical Center Groningen), Tim D. Spector(University of Eastern Finland), Unnur Þorsteinsdóttir(deCODE Genetics (Iceland)), Michael Stümvoll(IFB Adiposity Diseases), Jaakko Tuomilehto(Universität für Weiterbildung Krems), André G. Uitterlinden(University of Cambridge), Matti Uusitupa(Centre for Human Genetics), Pim van der Harst(University Medical Center Groningen), Mark Walker(Helmholtz Zentrum München), Henri Wallaschofski(Universitätsmedizin Greifswald), Nicholas J. Wareham(University of Cambridge), Hugh Watkins(Centre for Human Genetics), David R. Weir(King Abdulaziz University), H‐Erich Wichmann(Zimmer Biomet (Netherlands)), James F. Wilson(Helmholtz Zentrum München), Pieter Zanen(University of Maryland, Baltimore), Ingrid B. Borecki(St George's, University of London), Panos Deloukas(deCODE Genetics (Iceland)), Caroline S. Fox(Erasmus MC), Iris M. Heid(University of Michigan), Jeffrey R. O’Connell(University Medical Center Groningen), David P. Strachan(St George's, University of London), Kāri Stefánsson(deCODE Genetics (Iceland)), Cornelia M. van Duijn(The University of Queensland), Gonçalo R. Abecasis(University of Michigan), Lude Franke(University Medical Center Groningen), Timothy M. Frayling(University of Exeter), Mark I. McCarthy(University of North Carolina at Chapel Hill), Peter M. Visscher(Broad Institute), André Scherag(University Hospital of Lausanne), Cristen J. Willer(University of Cambridge), Michael Boehnke(University of North Carolina at Chapel Hill), Karen L. Mohlke(University of North Carolina at Chapel Hill), Cecilia M. Lindgren(Broad Institute), J. Beckmann(SIB Swiss Institute of Bioinformatics), Inês Barroso(University of Michigan), Kari E. North(University of North Carolina at Chapel Hill), Erik Ingelsson(Uppsala University), Joel N. Hirschhorn(Broad Institute), Ruth J. F. Loos(University of Cambridge), Elizabeth K. Speliotes(University of Michigan)

Nature

February 10, 2015

10.1038/nature14177

Cited by 4,885

Abstract

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