In Situ Genetic Correction of the Sickle Cell Anemia Mutation in Human Induced Pluripotent Stem Cells Using Engineered Zinc Finger Nucleases

Vittorio Sebastiano(California Institute for Regenerative Medicine), J. Keith Joung(Massachusetts General Hospital), Dana T. Yeo(Stanford University), Bahareh Haddad(Stanford University), James Angstman(Massachusetts General Hospital), Steven E. Artandi(Stanford University), Luís F.Z. Batista(Stanford University), John S. Hawkins(Stanford University), Cherie L. Ramirez(Harvard University), Cyd Khayter(Massachusetts General Hospital), Morgan L. Maeder(Harvard University), Marius Wernig(California Institute for Regenerative Medicine), Mathew J. Goodwin(Massachusetts General Hospital)
Stem Cells
September 2, 2011
10.1002/stem.718
Cited by 311

Related Papers

A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells
|Cell|2006|5.4k
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
|Nature|2007|4.2k
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
|Nature Biotechnology|2013|3.3k
CRISPR-Cas systems for editing, regulating and targeting genomes
|Nature Biotechnology|2014|3.2k
Efficient genome editing in zebrafish using a CRISPR-Cas system
|Nature Biotechnology|2013|3k