Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche

Hayley L. Belnoue-Davis(Centre for Human Genetics), Shazia Irshad(Centre for Human Genetics), Mukesh Bansal(Columbia University Irving Medical Center), Hannah Rafferty(Centre for Human Genetics), Tatjana Boitsova(Centre for Human Genetics), Chiara Bardella(Centre for Human Genetics), Emma Jaeger(Centre for Human Genetics), Annabelle Lewis(Centre for Human Genetics), Luke Freeman-Mills(Centre for Human Genetics), Francesc Castro-Giner(Centre for Human Genetics), Pedro Rodenas-Cuadrado(Centre for Human Genetics), Sreelakshmi Mallappa(St Mark's Hospital), Susan K. Clark(St Mark's Hospital), Huw Thomas(St Mark's Hospital), Rosemary Jeffery(Queen Mary University of London), Richard Poulsom(Queen Mary University of London), Manuel Rodriguez‐Justo(University College Hospital), Marco Novelli(University College Hospital), Runjan Chetty(University Health Network), Andrew Silver(Queen Mary University of London), Owen J. Sansom(Cancer Research UK Scotland Institute), Florian R. Greten(Georg Speyer Haus), Lai Mun Wang(John Radcliffe Hospital), James E. East(John Radcliffe Hospital), Ian Tomlinson(Centre for Human Genetics), Simon J. Leedham(Centre for Human Genetics)
Nature Medicine
November 24, 2014
Cited by 285

Abstract


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