Trabectedin (ET-743, Yondelis™) is a substrate for P-glycoprotein, but only high expression of P-glycoprotein confers the multidrug resistance phenotype

Jan H. Beumer(Johns Hopkins University), Olaf van Tellingen(Dutch Cancer Society), Mariët Ouwehand, Jos H. Beijnen(The Netherlands Cancer Institute), N. Franke(Princess Máxima Center), Jan H.M. Schellens(Utrecht University), Tessa Buckle(Leiden University Medical Center), Luis López Lázaro(Dr. Reddy's Laboratories (Switzerland))
Investigational New Drugs
April 5, 2006
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