2-Cycloalkyl phenoxyacetic acid CRTh2 receptor antagonists
David A. Sandham(Novartis (United States)), Caroline Wilson(University of Dundee), Louise Bidlake(Royal Society for the Prevention of Cruelty to Animals), Rachael Profit(Novartis (Switzerland)), Gurdip Bhalay(Royal Society for the Prevention of Cruelty to Animals), Brian Everatt(Royal Society for the Prevention of Cruelty to Animals), Katy S. Thompson(Royal Society for the Prevention of Cruelty to Animals), David C. Budd(Unknown), Steven Whitebread(Novartis (Switzerland)), Urs Baettig(Royal Society for the Prevention of Cruelty to Animals), Jodie Manini(Novartis (Switzerland)), Morris Tweed(Novartis (Switzerland)), Zarin Brown(Novartis (Switzerland)), Christoph Walker(King's College London), David Beer(Novartis (Switzerland)), Emma M. Campbell(Novartis (Switzerland)), Lucy Barker(Novartis (Switzerland)), Katharine L. Turner(Royal Society for the Prevention of Cruelty to Animals), Brian J. Cox(Royal Society for the Prevention of Cruelty to Animals), Rowan Stringer(Novartis (Switzerland)), Jennifer Willis(Novartis (Switzerland)), Gareth Williams(Novartis (Switzerland)), Simon J. Watson(Royal Society for the Prevention of Cruelty to Animals), David Harrison(Chelmsford and Essex Hospital), Catherine J. Leblanc(Royal Society for the Prevention of Cruelty to Animals), Gerald Dubois(Novartis (Switzerland)), Clive Aldcroft(Royal Society for the Prevention of Cruelty to Animals)
Cited by 18
Related Papers
Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C
|Cancer Discovery|2022|134
Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders
|Journal of Medicinal Chemistry|2023|62
Identification of a novel GPR81-selective agonist that suppresses lipolysis in mice without cutaneous flushing
|European Journal of Pharmacology|2014|54
Reversal of High Fat Diet-Induced Obesity, Systemic Inflammation, and Astrogliosis by the NLRP3 Inflammasome Inhibitors NT-0249 and NT-0796
|Journal of Pharmacology and Experimental Therapeutics|2024|51
Myocardial Hypertrophy Resulting from Low Dosage Isoproterenol Administration in Rats
|Experimental Biology and Medicine|1971|49