Consecutive Intramolecular Hydroamination/Asymmetric Transfer Hydrogenation under Relay Catalysis of an Achiral Gold Complex/Chiral Brønsted Acid Binary System

Zhi‐Yong Han(Hefei National Center for Physical Sciences at Nanoscale), Han Xiao(Hefei National Center for Physical Sciences at Nanoscale), Xiaohua Chen(Hefei National Center for Physical Sciences at Nanoscale), Liu‐Zhu Gong(University of Science and Technology of China)
Journal of the American Chemical Society
June 11, 2009
Cited by 371

Abstract

Consecutive hydroamination/asymmetric transfer hydrogenation under relay catalysis of an achiral gold complex/chiral Brønsted acid binary system has been described for the direct transformation of 2-(2-propynyl)aniline derivatives into tetrahydroquinolines with high enantiomeric purity.


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