The molecular biology of chronic myeloid leukemia
Michael W. Deininger(Hammersmith Hospital), John M. Goldman(Hammersmith Hospital), Junia V. Melo(Hammersmith Hospital)
Cited by 1,616
Abstract
Chronic myeloid leukemia (CML) is probably the most extensively studied human malignancy. The discovery of the Philadelphia (Ph) chromosome in 19601 as the first consistent chromosomal abnormality associated with a specific type of leukemia was a breakthrough in cancer biology. It took 13 years