Cellular Toxicity of Carbon-Based Nanomaterials
Arnaud Magrez(École Polytechnique Fédérale de Lausanne), Sandor Kasas(École Polytechnique Fédérale de Lausanne), Valérie Salicio(École Polytechnique Fédérale de Lausanne), Nathalie Pasquier(École Polytechnique Fédérale de Lausanne), Jin Won Seo(École Polytechnique Fédérale de Lausanne), Marco R. Celio(École Polytechnique Fédérale de Lausanne), Stefan Catsicas(École Polytechnique Fédérale de Lausanne), Beat Schwaller(École Polytechnique Fédérale de Lausanne), Lászlø Forró(École Polytechnique Fédérale de Lausanne)
Cited by 1,113
Abstract
The cellular toxicity of carbon-based nanomaterials was studied as a function of their aspect ratio and surface chemistry. These structures were multiwalled carbon nanotubes, carbon nanofibers, and carbon nanoparticles. Their toxicity was tested in vitro on lung tumor cells. Our work clearly indicated that these materials are toxic while the hazardous effect is size-dependent. Moreover, cytotoxicity is enhanced when the surface of the particles is functionalized after an acid treatment.
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