Survival and Histopathological Study of Animals Bearing EhrlichTumor Treated With a Rhodium(II) Amidate

Breno Pannia Espósito(Universidade de São Paulo), Szulim Ber Zyngier(Universidade de São Paulo), Renato Najjar(Universidade de São Paulo), Roberto Pinto Paes(Faculdade de Ciências Médicas da Santa Casa de São Paulo), Suely M. Ykko Ueda(Faculdade de Ciências Médicas da Santa Casa de São Paulo), José Carlos A. Barros(Faculdade de Ciências Médicas da Santa Casa de São Paulo)
Metal-Based Drugs
October 9, 1998
10.1155/mbd.1999.17
Cited by 5Open Access
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Abstract

The survival of 90% of a tumor-bearing population treated with the complex Rh(2) (CF(3)CONH)(4) was examined and the pharmacological parameter Surv(90) determined. Histopathological alterations raised for this drug in several tissues were studied in Balb-c mice. A Surv(90) dose of 3.8x 10(-5) mol/kg was found.

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