p53, guardian of the genomeDavid P. Lane(University of Dundee)NatureJuly 1, 199210.1038/358015a0Cited by 5,105SaveCiteExport RISWatch citationsAbstractRelated Papersp53 Mutations in Human CancersMonica Hollstein, David Sidransky, Bert Vogelstein et al.|Science|1991|8.1kMice deficient for p53 are developmentally normal but susceptible to spontaneous tumoursLawrence A. Donehower, Michele Harvey, Betty L. Slagle et al.|Nature|1992|4.7kParticipation of p53 protein in the cellular response to DNA damage.Michael B. Kastan, Onyinye Onyekwere, D Sidransky et al.|PubMed|1991|3.8kThe mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivationJamil Momand, Gerard P. Zambetti, David C. Olson et al.|Cell|1992|3.1kWild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6Elisheva Yonish-Rouach, Dalia Resnftzky, Joseph Lotem et al.|Nature|1991|2.1k